Zhou Katherine I, Pan Tao
Medical Scientist Training Program, The University of Chicago, Chicago, IL 60637, USA.
Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA.
Mol Cell. 2016 Jul 21;63(2):183-185. doi: 10.1016/j.molcel.2016.07.005.
In this issue of Molecular Cell, Wang et al. (2016a) report crystal structures of the core of the METTL3/METTL14 m(6)A methyltransferase complex and propose how the two subunits interact and cooperate to bind and methylate RNA.
在本期《分子细胞》杂志中,王等人(2016年a)报道了METTL3/METTL14 m⁶A甲基转移酶复合体核心的晶体结构,并提出了这两个亚基如何相互作用与协作以结合RNA并使其甲基化。