X射线放射技师血液淋巴细胞的细胞遗传学分析。

Cytogenetic analysis of blood lymphocytes from X-ray radiographers.

作者信息

Shubber E K, al-Shaikhly A W

机构信息

Department of Biochemistry, Faculty of Agriculture and Biology, Baghdad, Iraq.

出版信息

Int Arch Occup Environ Health. 1989;61(6):385-9. doi: 10.1007/BF00381029.

DOI:10.1007/BF00381029

PMID:2744869

Abstract

Cytogenetic analysis was performed on blood lymphocytes from 46 healthy radiographers exposed to an annual dose of X-rays below the Maximum Permissible Occupational Limit (MPOL 5 rem/year) for a period ranging from 6 months to 26 years. Total chromosomal aberrations including dicentric and ring forms was 10.18%, which was significantly higher (P less than 0.01) than that (1.17%) of 50 healthy unexposed individuals (controls). A significant increase in the frequency of SCEs in cells from radiographers (11.2 +/- 0.9 SCE/cell) was noticed as compared with the controls (6.9 +/- 0.2 SCE/cell). There was a significant difference in lymphocyte proliferation between the two groups. These results indicate the importance of monitoring the health status of radiation workers.

摘要

对46名健康的放射技师的血液淋巴细胞进行了细胞遗传学分析，这些放射技师每年接受的X射线剂量低于最大允许职业剂量（MPOL 5雷姆/年），接触时间为6个月至26年。包括双着丝粒和环状形式在内的总染色体畸变率为10.18%，显著高于50名未接触辐射的健康个体（对照组）的畸变率（1.17%）（P<0.01）。与对照组（6.9±0.2个姐妹染色单体交换/细胞）相比，发现放射技师细胞中的姐妹染色单体交换频率显著增加（11.2±0.9个姐妹染色单体交换/细胞）。两组之间的淋巴细胞增殖存在显著差异。这些结果表明监测辐射工作人员健康状况的重要性。