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X射线放射技师血液淋巴细胞的细胞遗传学分析。

Cytogenetic analysis of blood lymphocytes from X-ray radiographers.

作者信息

Shubber E K, al-Shaikhly A W

机构信息

Department of Biochemistry, Faculty of Agriculture and Biology, Baghdad, Iraq.

出版信息

Int Arch Occup Environ Health. 1989;61(6):385-9. doi: 10.1007/BF00381029.

DOI:10.1007/BF00381029
PMID:2744869
Abstract

Cytogenetic analysis was performed on blood lymphocytes from 46 healthy radiographers exposed to an annual dose of X-rays below the Maximum Permissible Occupational Limit (MPOL 5 rem/year) for a period ranging from 6 months to 26 years. Total chromosomal aberrations including dicentric and ring forms was 10.18%, which was significantly higher (P less than 0.01) than that (1.17%) of 50 healthy unexposed individuals (controls). A significant increase in the frequency of SCEs in cells from radiographers (11.2 +/- 0.9 SCE/cell) was noticed as compared with the controls (6.9 +/- 0.2 SCE/cell). There was a significant difference in lymphocyte proliferation between the two groups. These results indicate the importance of monitoring the health status of radiation workers.

摘要

对46名健康的放射技师的血液淋巴细胞进行了细胞遗传学分析,这些放射技师每年接受的X射线剂量低于最大允许职业剂量(MPOL 5雷姆/年),接触时间为6个月至26年。包括双着丝粒和环状形式在内的总染色体畸变率为10.18%,显著高于50名未接触辐射的健康个体(对照组)的畸变率(1.17%)(P<0.01)。与对照组(6.9±0.2个姐妹染色单体交换/细胞)相比,发现放射技师细胞中的姐妹染色单体交换频率显著增加(11.2±0.9个姐妹染色单体交换/细胞)。两组之间的淋巴细胞增殖存在显著差异。这些结果表明监测辐射工作人员健康状况的重要性。

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本文引用的文献

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Radiat Res. 1984 Oct;100(1):47-54.