MacDonell Sue O, Miller Jody C, Harper Michelle J, Waters Debra L, Houghton Lisa A
1Department of Human Nutrition,University of Otago,PO Box 56,Dunedin 9054,New Zealand.
2Department of Medicine/School of Physiotherapy,Dunedin School of Medicine,University of Otago,Dunedin,New Zealand.
Public Health Nutr. 2016 Dec;19(18):3349-3360. doi: 10.1017/S1368980016001683. Epub 2016 Jul 25.
The provision of prescribed vitamin D to all aged-care residents has been implemented in New Zealand as part of a government-led falls prevention programme. To our knowledge, there has been no evaluation of this universal programme on vitamin D status and functional and health outcomes. Thus, we aimed to determine 25-hydroxyvitamin D (25(OH)D) concentrations and their predictors in aged-care residents across the country and to investigate whether the government-funded programme was associated with adequate vitamin D status.
Cross-sectional survey of sociodemographic, biochemical, anthropometric, dietary and health characteristics. Blood samples were analysed for serum 25(OH)D and other biochemical measures. Multiple regression was used to examine predictors of vitamin D status.
Sixteen residential aged-care facilities throughout New Zealand.
Residents aged ≥60 years with residency duration >12 weeks (n 309).
Mean serum 25(OH)D was 89·9 (95 % CI 85·2, 94·5) nmol/l and monthly supplements (1250 µg (50 000 IU)) were taken by 75 % of all residents. Of those not taking a funded supplement, 65·3 % had serum 25(OH)D 125 nmol/l.
Residents taking supplemental vitamin D had adequate vitamin D status; however monitoring of long-term supplementation should be considered, due to the high proportion of participants with high serum 25(OH)D levels.
在新西兰,向所有老年护理机构居民提供规定剂量的维生素D已作为政府主导的预防跌倒计划的一部分得以实施。据我们所知,尚未有对这一普及计划在维生素D状态以及功能和健康结局方面的评估。因此,我们旨在确定全国老年护理机构居民的25-羟基维生素D(25(OH)D)浓度及其预测因素,并调查政府资助的计划是否与充足的维生素D状态相关。
对社会人口统计学、生化、人体测量学、饮食和健康特征进行横断面调查。对血样进行血清25(OH)D和其他生化指标分析。采用多元回归分析来检查维生素D状态的预测因素。
新西兰各地的16家老年护理机构。
年龄≥60岁且居住时间>12周的居民(n = 309)。
血清25(OH)D的平均水平为89·9(95%可信区间85·2, 94·5)nmol/l,75%的居民服用每月补充剂(1250μg(50 000 IU))。在未服用资助补充剂的居民中,65·3%的人血清25(OH)D<50 nmol/l,125 nmol/l。
服用补充维生素D的居民维生素D状态充足;然而,鉴于血清25(OH)D水平高的参与者比例较高,应考虑对长期补充情况进行监测。