Djurica Dragana, Holt Roberta R, Ren Jingyan, Shindel Alan W, Hackman Robert M, Keen Carl L
1Department of Nutrition,University of California, Davis,One Shields Avenue,Davis,CA 95616,USA.
2Department of Urology,University of California Davis Medical Center;4860 Y Street,Suite 2200 Sacramento,CA 95817,USA.
Br J Nutr. 2016 Aug;116(4):639-47. doi: 10.1017/S0007114516002348.
Previous studies have shown that the intake of freeze-dried strawberry powder (FDSP) improves select markers of cardiovascular health in adults with cardiovascular risk factors; however, whether these improvements can be observed in at-risk adolescents is unknown. A randomised, double-blind, cross-over study enrolled twenty-five overweight or obese males, aged 14-18 years, to consume 50 g of a FDSP or a control powder, daily for 1 week. Before and after each test period, measures of microvascular function, plasma nitrate/nitrite, platelet reactivity and blood lipids were collected at baseline and acutely 1 h after FDSP intake. Acute plasma nitrate/nitrite levels increased 1 h after consuming the FDSP during Study Visit 1 before daily FDSP intake (P<0·001) and during Study Visit 2 after 1 week of FDSP intake (P<0·001) compared with control powder intake. As a group, fasting nitrate/nitrite levels did not significantly change after 1 week of control or FDSP intake. However, for those individuals where fasting nitrate levels increased after short-term FDSP intake compared with controls, an increase in reactive hyperaemia index (RHI) was observed (P=0·014), whereas RHI was unchanged in those individuals who did not have a significant increase in nitrate (P=0·396). Taken together, these data support the concept that strawberries can provide vascular health benefits to heavier adolescent males.
先前的研究表明，摄入冻干草莓粉（FDSP）可改善有心血管危险因素的成年人的某些心血管健康指标；然而，这些改善是否能在有风险的青少年中观察到尚不清楚。一项随机、双盲、交叉研究招募了25名年龄在14 - 18岁的超重或肥胖男性，让他们每天食用50克FDSP或对照粉末，持续1周。在每个测试期前后，在基线以及摄入FDSP后1小时急性采集微血管功能、血浆硝酸盐/亚硝酸盐、血小板反应性和血脂的测量值。与摄入对照粉末相比，在每日摄入FDSP前的研究访视1期间（P<0·001）以及在摄入FDSP 1周后的研究访视2期间（P<0·001），摄入FDSP后1小时急性血浆硝酸盐/亚硝酸盐水平升高。作为一个群体，在摄入对照或FDSP 1周后，空腹硝酸盐/亚硝酸盐水平没有显著变化。然而，对于那些与对照组相比短期摄入FDSP后空腹硝酸盐水平升高的个体，观察到反应性充血指数（RHI）增加（P = 0·014），而在硝酸盐没有显著增加的个体中RHI没有变化（P = 0·396）。综上所述，这些数据支持草莓可以为体重较重的青少年男性提供血管健康益处这一概念。
