Xiao Hui-Hui, Zhang Yan, Cooper Raymond, Yao Xin-Sheng, Wong Man-Sau
State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), Shenzhen Research Institute of The Hong Kong Polytechnic University, Shenzhen, 518057 China ; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.
Spine Research Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200032 China.
Chin Med. 2016 Jul 28;11:36. doi: 10.1186/s13020-016-0106-9. eCollection 2016.
Sambucus williamsii Hance (Jiegumu) is traditionally used in Chinese medicine to treat bone and joint diseases. The major phytochemicals in S. williamsii are lignans, terpenoids, and phenolic acids, together with trace amounts of essential oils, minerals, amino acids, and natural pigments. In this review, a database search for studies published from 1990 to November 2015 was conducted using PubMed, the China Academic Journals Full-Text Database, and Google Scholar with the keywords "Sambucus williamsii Hance", "Sambucus williamsii", "Sambucus williamsii + clinic", "Sambucus williamsii + biology", "Sambucus williamsii + chemicals", and "Jiegumu", which covered chemical studies, cell culture studies, animal experiments, and clinical studies. This article reviewed the compounds isolated from S. williamsii that may reduce the risk of cancer, and exert antifungal, antioxidant, anti-inflammatory, bone fracture healing, and antiosteoporotic effects.
接骨木(Sambucus williamsii Hance)在传统中医中用于治疗骨与关节疾病。接骨木中的主要植物化学成分是木脂素、萜类化合物和酚酸,还有微量的精油、矿物质、氨基酸和天然色素。在本综述中,使用PubMed、中国学术期刊全文数据库和谷歌学术,以关键词“接骨木(Sambucus williamsii Hance)”、“接骨木(Sambucus williamsii)”、“接骨木(Sambucus williamsii)+临床”、“接骨木(Sambucus williamsii)+生物学”、“接骨木(Sambucus williamsii)+化学物质”和“接骨木”进行数据库检索,检索1990年至2015年11月发表的研究,涵盖化学研究、细胞培养研究、动物实验和临床研究。本文综述了从接骨木中分离出的可能降低癌症风险、发挥抗真菌、抗氧化、抗炎、促进骨折愈合和抗骨质疏松作用的化合物。