Saceda-Corralo D, Grimalt R, Fernández-Crehuet P, Clemente A, Bernárdez C, García-Hernandez M J, Arias-Santiago S, Rodrigues-Barata A R, Rodríguez-Pichardo A, García-Lora E, Jaén P, Camacho F M, Vañó-Galván S
Dermatology Department, Ramon y Cajal Hospital, Madrid, Spain.
Dermatology Department, Universitat de Barcelona, Universitat Internacional de Catalunya, Madrid, Spain.
J Eur Acad Dermatol Venereol. 2017 Jan;31(1):187-192. doi: 10.1111/jdv.13896. Epub 2016 Sep 12.
Alopecia areata on the beard area (BAA) is a common clinical manifestation, but there are no studies about its characteristics.
To describe the epidemiology, comorbidities, clinical presentation, evolution, diagnostic findings and therapeutic choices in a series of patients with BAA.
This retrospective multicentre review included patients diagnosed with BAA as the first and unique clinical manifestation with at least 12 months of follow-up. Diagnosis was performed based on the typical clinical features. Extra-beard involvement was monitored in all cases.
Overall, 55 male patients with a mean age of 39.1 years (range 20-74) were included. Twenty-five patients (45.5%) developed alopecia of the scalp during follow-up and more than 80% of cases appeared in the first 12.4 months. Clinical presentation of AA on the scalp was patchy AA (less than 5 patches) (52%), multifocal AA (28%), AA totalis (12%) and AA universalis (8%). Multivariate analysis revealed a trend of association between scalp involvement and family history of AA without statistical significance.
According to this study, BAA may progress to scalp AA in a significant number of patients (45.5% of the patients with a follow-up interval of at least 12 months). In the group of patients who developed scalp AA, 80% of them did it within the first 12 months, so follow-up of patients with BAA is highly encouraged.
胡须区斑秃（BAA）是一种常见的临床表现，但尚无关于其特征的研究。
描述一系列胡须区斑秃患者的流行病学、合并症、临床表现、病情演变、诊断结果及治疗选择。
这项回顾性多中心研究纳入了诊断为胡须区斑秃且为首发及唯一临床表现、随访至少12个月的患者。诊断基于典型临床特征。所有病例均监测胡须区以外部位的受累情况。
共纳入55例男性患者，平均年龄39.1岁（范围20 - 74岁）。25例患者（45.5%）在随访期间出现头皮脱发，80%以上的病例在最初的12.4个月内出现。头皮斑秃的临床表现为斑片状斑秃（少于5处脱发斑）（52%）、多灶性斑秃（28%）、全秃（12%）和普秃（8%）。多变量分析显示头皮受累与斑秃家族史之间存在关联趋势，但无统计学意义。
根据本研究，相当一部分胡须区斑秃患者（随访间隔至少12个月的患者中45.5%）可能进展为头皮斑秃。在出现头皮斑秃的患者组中，80%在最初12个月内发生，因此强烈建议对胡须区斑秃患者进行随访。
