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1976年和2013年疫情中两株扎伊尔埃博拉病毒气溶胶稳定性的比较。

Comparison of the Aerosol Stability of 2 Strains of Zaire ebolavirus From the 1976 and 2013 Outbreaks.

作者信息

Fischer Robert J, Bushmaker Trenton, Judson Seth, Munster Vincent J

机构信息

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana.

David Geffen School of Medicine at UCLA.

出版信息

J Infect Dis. 2016 Oct 15;214(suppl 3):S290-S293. doi: 10.1093/infdis/jiw193. Epub 2016 Aug 8.

DOI:10.1093/infdis/jiw193
PMID:27503365
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5050463/
Abstract

The largest outbreak of Ebola virus disease began in Guéckédou, Guinea, West Africa, in December 2013 and rapidly spread to major population centers in 3 West African countries. Early reports in some scientific and public media speculated that the virus had evolved to more effectively transmit between humans. One route of transmission postulated was aerosol transmission, although there was little epidemiological evidence to support this claim. This study investigates the viability of 2 Zaire ebolavirus strains within aerosols at 22°C and 80% relative humidity over time. The results presented here indicate that there is no difference in virus stability between the 2 strains and that viable virus can be recovered from an aerosol 180 minutes after it is generated.

摘要

2013年12月,埃博拉病毒病最大规模的疫情在西非几内亚的盖凯杜爆发,并迅速蔓延至3个西非国家的主要人口中心。一些科学和公共媒体的早期报道推测,该病毒已进化为能在人与人之间更有效地传播。尽管几乎没有流行病学证据支持这一说法,但推测的一种传播途径是气溶胶传播。本研究调查了两种扎伊尔埃博拉病毒毒株在22°C和80%相对湿度条件下随时间在气溶胶中的存活能力。此处呈现的结果表明,两种毒株之间的病毒稳定性没有差异,并且在气溶胶产生180分钟后仍可从其中回收活病毒。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/921b/5050463/25f3eecb4e2b/jiw19301.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/921b/5050463/25f3eecb4e2b/jiw19301.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/921b/5050463/25f3eecb4e2b/jiw19301.jpg

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