Moleti A, Sisto R
Physics Department, University of Roma Tor Vergata, Via della Ricerca Scientifica, 1, 00133, Rome, Italy.
INAIL Research, Via di Fontana Candida 1, 00044, Monteporzio Catone (RM), Italy.
J Assoc Res Otolaryngol. 2016 Oct;17(5):393-401. doi: 10.1007/s10162-016-0580-x. Epub 2016 Aug 9.
The generation of stimulus-frequency otoacoustic emission (SFOAE) residuals in humans is analyzed both theoretically and experimentally to investigate the relation between the frequency difference between the probe and the suppressor tone and the localization of the residual source. Experimental measurements of the SFOAE residual were performed using suppressors of increasing frequency to separate the otoacoustic response from the probe stimulus. From the response to the probe alone, the SFOAE response was also estimated, using spectral smoothing, and compared with the residuals obtained for different frequency suppressors. A nonlinear delayed-stiffness active cochlear model was used to compute the spatial distribution of the residual sources according to a recent model of the local reflectivity from roughness, as a function of the suppressor frequency. The simulations clarified the role of high-frequency suppressors, showing that in humans, with increasing suppressor frequency, the generation region of the residual is only slightly basally shifted with respect to the case of a near-frequency suppressor, near the basal edge of the peak of the resonant basilar membrane response. As a consequence, the hierarchy among different-delay components correspondingly changes, gradually favoring short-delay components, with increasing suppressor frequency. Good agreement between the experimental and theoretical dependence of the level of otoacoustic components of different delay on the frequency shift between probe and suppressor confirms the validity of this interpretation.
对人类中刺激频率耳声发射(SFOAE)残余信号的产生进行了理论和实验分析,以研究探测音与抑制音之间的频率差异与残余信号源定位之间的关系。使用频率不断增加的抑制音来分离探测刺激的耳声响应,从而对SFOAE残余信号进行实验测量。仅根据对探测音的响应,利用频谱平滑法估算出SFOAE响应,并与不同频率抑制音下获得的残余信号进行比较。根据最近提出的粗糙度局部反射率模型,利用非线性延迟-刚度有源耳蜗模型计算残余信号源的空间分布,该分布是抑制音频率的函数。模拟结果阐明了高频抑制音的作用,表明在人类中,随着抑制音频率的增加,残余信号的产生区域相对于近频抑制音的情况仅在基底方向上略有偏移,靠近共振基底膜响应峰值的基底边缘。因此,不同延迟成分之间的层次关系相应地发生变化,随着抑制音频率的增加,逐渐有利于短延迟成分。不同延迟的耳声成分水平对探测音与抑制音之间频率偏移的实验和理论依赖性之间的良好一致性证实了这种解释的有效性。