Fröhlich Hanna, Herrmann Kristina, Franke Jennifer, Karimi Alamara, Täger Tobias, Cebola Rita, Katus Hugo A, Zugck Christian, Frankenstein Lutz
Tex Heart Inst J. 2016 Aug 1;43(4):297-304. doi: 10.14503/THIJ-15-5200. eCollection 2016 Aug.
Periodontal disease has been associated with an increased risk of cardiovascular events. The purpose of our study was to investigate whether a correlation between periodontitis and chronic heart failure exists, as well as the nature of the underlying cause. We enrolled 71 patients (mean age, 54 ± 13 yr; 56 men) who had stable chronic heart failure; all underwent complete cardiologic and dental evaluations. The periodontal screening index was used to quantify the degree of periodontal disease. We compared the findings to those in the general population with use of data from the 4th German Dental Health Survey. Gingivitis, moderate periodontitis, and severe periodontitis were present in 17 (24%), 17 (24%), and 37 (52%) patients, respectively. Severe periodontitis was more prevalent among chronic heart failure patients than in the general population. In contrast, moderate periodontitis was more prevalent in the general population (P <0.00001). The severity of periodontal disease was not associated with the cause of chronic heart failure or the severity of heart failure symptoms. Six-minute walking distance was the only independent predictor of severe periodontitis. Periodontal disease is highly prevalent in chronic heart failure patients regardless of the cause of heart failure. Prospective trials are warranted to clarify the causal relationship between both diseases.
牙周疾病与心血管事件风险增加有关。我们研究的目的是调查牙周炎与慢性心力衰竭之间是否存在关联以及潜在病因的性质。我们纳入了71例患有稳定慢性心力衰竭的患者(平均年龄54±13岁;56例男性);所有患者均接受了全面的心脏和牙科评估。采用牙周筛查指数来量化牙周疾病的程度。我们使用来自第四次德国牙科健康调查的数据,将研究结果与普通人群的结果进行比较。17例(24%)、17例(24%)和37例(52%)患者分别存在牙龈炎、中度牙周炎和重度牙周炎。重度牙周炎在慢性心力衰竭患者中比在普通人群中更为普遍。相比之下,中度牙周炎在普通人群中更为普遍(P<0.00001)。牙周疾病的严重程度与慢性心力衰竭的病因或心力衰竭症状的严重程度无关。6分钟步行距离是重度牙周炎的唯一独立预测因素。无论心力衰竭的病因如何,牙周疾病在慢性心力衰竭患者中都非常普遍。有必要进行前瞻性试验以阐明这两种疾病之间的因果关系。