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[研究领域标准(Rdoc)、还原论与临床精神病学]

[The Research Domain Criteria (Rdoc), reductionism and clinical psychiatry].

作者信息

Faucher Luc, Goyer Simon

机构信息

Département de philosophie, Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, Montréal, Québec, Canada, H3C 3P8.

出版信息

Rev Synth. 2016 Dec;137(1-2):117-49. doi: 10.1007/s11873-016-0292-8.

DOI:10.1007/s11873-016-0292-8
PMID:27550461
Abstract

The focus of the advocates of the Research Domain Critria (RDoC) on faulty brain circuits has led some to suspect it of being a reductionist enterprise. And because RDoC will eventually impact clinical psychiatry, some have feared that it will transform clinical psychiatry in a mindless and applied neurobehavioral science. We argue that if RDoC is officially endorsing a kind of reductionism, the particular kind of reductionism it endorses is not suffering from the shortcomings of more classical forms of reductionism. Because of that, at least in principle, RDoC could enrich rather than impoverish clinical psychiatry. This paper raises few potential problems of the RDoC for clinical psychiatry caused by its implicit epistemological reductionism.

摘要

研究领域标准(RDoC)的倡导者将重点放在有缺陷的脑回路方面,这使得一些人怀疑它是一个还原论的事业。而且由于RDoC最终会影响临床精神病学,一些人担心它会将临床精神病学转变为一门盲目的应用神经行为科学。我们认为,如果RDoC正式支持某种还原论,那么它所支持的那种还原论并不存在更经典形式的还原论的缺点。正因为如此,至少在原则上,RDoC可以丰富而不是削弱临床精神病学。本文提出了RDoC因其隐含的认识论还原论给临床精神病学带来的一些潜在问题。

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本文引用的文献

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The brain disease model of addiction: is it supported by the evidence and has it delivered on its promises?成瘾的脑疾病模型:有证据支持吗?它兑现承诺了吗?
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Research Domain Criteria: toward future psychiatric nosologies.研究领域标准:迈向未来的精神疾病分类学
Dialogues Clin Neurosci. 2015 Mar;17(1):89-97. doi: 10.31887/DCNS.2015.17.1/bcuthbert.
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Why is the Diagnostic and Statistical Manual of Mental Disorders so hard to revise? Path-dependence and "lock-in" in classification.
为什么《精神疾病诊断与统计手册》如此难以修订?分类中的路径依赖和“锁定”现象。
Stud Hist Philos Biol Biomed Sci. 2015 Jun;51:1-10. doi: 10.1016/j.shpsc.2015.03.001. Epub 2015 Mar 31.
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Application of the Research Domain Criteria (RDoC) framework to eating disorders: emerging concepts and research.应用研究领域标准(RDoC)框架于进食障碍:新兴概念与研究。
Curr Psychiatry Rep. 2015 May;17(5):30. doi: 10.1007/s11920-015-0572-2.
5
Failed drug discovery in psychiatry: time for human genome-guided solutions.精神病学药物研发失败:是时候采用人类基因组指导的解决方案了。
Trends Cogn Sci. 2015 Apr;19(4):183-7. doi: 10.1016/j.tics.2015.02.002. Epub 2015 Feb 27.
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Effects of biological explanations for mental disorders on clinicians' empathy.精神障碍生物学解释对临床医生同理心的影响。
Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17786-90. doi: 10.1073/pnas.1414058111. Epub 2014 Dec 1.
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Transl Psychiatry. 2014 Sep 16;4(9):e444. doi: 10.1038/tp.2014.83.
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Biol Psychiatry. 2014 Sep 1;76(5):350-3. doi: 10.1016/j.biopsych.2014.01.006.
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Studying hallucinations within the NIMH RDoC framework.在国家心理健康研究所(NIMH)的研究领域标准(RDoC)框架内研究幻觉。
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Am J Psychiatry. 2014 Sep;171(9):931-8. doi: 10.1176/appi.ajp.2014.13111539.