妊娠期淋巴瘤的管理
Management of lymphoma in pregnancy.
作者信息
Hodby K, Fields P A
机构信息
Department of Haematology , Guys and St Thomas' Hospital , St Thomas Street, London SE1 9RT , UK.
出版信息
Obstet Med. 2009 Jun;2(2):46-51. doi: 10.1258/om.2009.090007. Epub 2009 May 22.
Abstract
One in every thousand pregnancies is complicated by a concurrent diagnosis of cancer. Lymphoma is currently the fourth most common malignancy diagnosed during pregnancy and its incidence is rising. The diagnosis and management of any malignancy during pregnancy is clearly a clinical and emotional minefield for both patients and health-care professionals. The major challenge is to optimize medical treatment offered to the mother, while limiting the impact on the fetus. Given the relative rarity of the situation, current practice is guided by case reports and personal experience of management of similar patients. Our centre has a large and busy lymphoma practice, and has cared for several women diagnosed with a variety of subtypes of lymphoma over the years. This review aims to summarize current opinion about best practice regarding these patients and discusses options available from the current literature.
摘要
每千次怀孕中就有一次并发癌症。淋巴瘤是目前孕期诊断出的第四大常见恶性肿瘤，且其发病率正在上升。孕期任何恶性肿瘤的诊断和管理，对患者和医护人员来说显然都是一个临床和情感上的雷区。主要挑战在于优化为母亲提供的医疗治疗，同时限制对胎儿的影响。鉴于这种情况相对罕见，目前的做法是基于病例报告和对类似患者管理的个人经验。我们中心有大量繁忙的淋巴瘤诊疗业务，多年来已经照料过几位被诊断患有各种淋巴瘤亚型的女性。这篇综述旨在总结关于这些患者最佳治疗方法的当前观点，并讨论现有文献中可供选择的方案。
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