Pereira R M, Gonçalves C R, Bueno C, Meirelles E de S, Cossermelli W, de Oliveira R M
Department of Rheumatology, University of São Paulo School of Medicine, Brasil.
Clin Rheumatol. 1989 Jun;8(2):289-91. doi: 10.1007/BF02030089.
A high incidence of anticardiolipin antibodies were detected in 7 of 20 patients (35%) with Behçet's Syndrome. Three patients had IgG-ab, three had IgM-ab and one had both IgG and IgM antibodies. IgG-ACA was detected mainly in patients with ocular disease (30%) and one of them also has cerebral vascular disease. A lower incidence of ACA was found in the patients taking steroids compared with the ones taking other drugs. This work draws attention to the more severe disease present in patients with ACA and also the possibility of such tests become negative in patients taking immunosuppressive drugs.
在20例白塞病患者中,7例(35%)检测到抗心磷脂抗体的高发生率。3例患者有IgG抗体,3例有IgM抗体,1例同时有IgG和IgM抗体。IgG-ACA主要在眼部疾病患者中检测到(30%),其中1例还患有脑血管疾病。与服用其他药物的患者相比,服用类固醇的患者中ACA的发生率较低。这项研究提请注意ACA患者中存在的更严重疾病,以及服用免疫抑制药物的患者此类检测可能呈阴性的可能性。