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白塞病中的抗心磷脂抗体:病情更严重的一个预测指标。

Anticardiolipin antibodies in Behçet's syndrome: a predictor of a more severe disease.

作者信息

Pereira R M, Gonçalves C R, Bueno C, Meirelles E de S, Cossermelli W, de Oliveira R M

机构信息

Department of Rheumatology, University of São Paulo School of Medicine, Brasil.

出版信息

Clin Rheumatol. 1989 Jun;8(2):289-91. doi: 10.1007/BF02030089.

DOI:10.1007/BF02030089
PMID:2758775
Abstract

A high incidence of anticardiolipin antibodies were detected in 7 of 20 patients (35%) with Behçet's Syndrome. Three patients had IgG-ab, three had IgM-ab and one had both IgG and IgM antibodies. IgG-ACA was detected mainly in patients with ocular disease (30%) and one of them also has cerebral vascular disease. A lower incidence of ACA was found in the patients taking steroids compared with the ones taking other drugs. This work draws attention to the more severe disease present in patients with ACA and also the possibility of such tests become negative in patients taking immunosuppressive drugs.

摘要

在20例白塞病患者中,7例(35%)检测到抗心磷脂抗体的高发生率。3例患者有IgG抗体,3例有IgM抗体,1例同时有IgG和IgM抗体。IgG-ACA主要在眼部疾病患者中检测到(30%),其中1例还患有脑血管疾病。与服用其他药物的患者相比,服用类固醇的患者中ACA的发生率较低。这项研究提请注意ACA患者中存在的更严重疾病,以及服用免疫抑制药物的患者此类检测可能呈阴性的可能性。

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1
Anticardiolipin antibodies in Behçet's syndrome: a predictor of a more severe disease.白塞病中的抗心磷脂抗体:病情更严重的一个预测指标。
Clin Rheumatol. 1989 Jun;8(2):289-91. doi: 10.1007/BF02030089.
2
Anticardiolipin antibodies: occurrence in Behçet's syndrome.抗心磷脂抗体:在白塞病中的出现情况。
Ann Rheum Dis. 1984 Oct;43(5):746-8. doi: 10.1136/ard.43.5.746.
3
Anticardiolipin antibodies in Adamantiades-Behçet's disease.白塞病中的抗心磷脂抗体
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Anticardiolipin antibodies in Behçet's disease.白塞病中的抗心磷脂抗体。
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Hautarzt. 1992 Mar;43(3):130-3.
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[Anticardiolipin antibodies in Behçet's disease].[白塞病中的抗心磷脂抗体]
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Behçet's Disease as a Model of Venous Thrombosis.白塞病作为静脉血栓形成的模型
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本文引用的文献

1
Anticardiolipin antibodies: occurrence in Behçet's syndrome.抗心磷脂抗体:在白塞病中的出现情况。
Ann Rheum Dis. 1984 Oct;43(5):746-8. doi: 10.1136/ard.43.5.746.
2
Thrombosis in systemic lupus erythematosus: striking association with the presence of circulating lupus anticoagulant.系统性红斑狼疮中的血栓形成:与循环狼疮抗凝物的存在显著相关。
Br Med J (Clin Res Ed). 1983 Oct 8;287(6398):1021-3. doi: 10.1136/bmj.287.6398.1021.
3
Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus.
患有下腔静脉血栓形成的白塞病患者的抗心磷脂(aCL)抗体
Clin Rheumatol. 1997 Jan;16(1):96-8. doi: 10.1007/BF02238771.
4
Absence of antiphospholipid antibodies in Behçet's disease.白塞病中抗磷脂抗体的缺失。
Ann Rheum Dis. 1993 Aug;52(8):623. doi: 10.1136/ard.52.8.623-a.
抗心磷脂抗体:通过放射免疫测定法检测及其与系统性红斑狼疮中血栓形成的关联
Lancet. 1983 Nov 26;2(8361):1211-4. doi: 10.1016/s0140-6736(83)91267-9.
4
Negative anticardiolipin antibodies and vascular complications in Behçet's syndrome.白塞病中的抗心磷脂抗体阴性与血管并发症
Ann Rheum Dis. 1985 Oct;44(10):725-6. doi: 10.1136/ard.44.10.725.
5
Anti-phospholipid antibodies.抗磷脂抗体
Clin Rheum Dis. 1985 Dec;11(3):591-609.
6
Antibody to cardiolipin as a predictor of fetal distress or death in pregnant patients with systemic lupus erythematosus.抗心磷脂抗体作为系统性红斑狼疮孕妇胎儿窘迫或死亡的预测指标。
N Engl J Med. 1985 Jul 18;313(3):152-6. doi: 10.1056/NEJM198507183130304.
7
Chlorpromazine-induced anticardiolipin antibodies and lupus anticoagulant: absence of thrombosis.氯丙嗪诱导的抗心磷脂抗体和狼疮抗凝物:无血栓形成。
Am J Hematol. 1988 Apr;27(4):272-5. doi: 10.1002/ajh.2830270408.
8
[Anticardiolipin antibodies in Behçet's disease].[白塞病中的抗心磷脂抗体]
Presse Med. 1986;15(27):1281.
9
Behcet's syndrome in 32 patients in Yorkshire.约克郡32例白塞病患者。
Ann Rheum Dis. 1977 Dec;36(6):491-99. doi: 10.1136/ard.36.6.491.