用于肌腱愈合与再生的纳米颗粒：文献综述
Nanoparticles for Tendon Healing and Regeneration: Literature Review.
作者信息
Parchi Paolo D, Vittorio Orazio, Andreani Lorenzo, Battistini Pietro, Piolanti Nicola, Marchetti Stefano, Poggetti Andrea, Lisanti Michele
机构信息
First Orthopaedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa Pisa, Italy.
Lowy Cancer Research Centre, Children's Cancer Institute Australia, UNSW AustraliaSydney, NSW, Australia; Australian Centre for NanoMedicine, UNSW AustraliaSydney, NSW, Australia.
出版信息
Front Aging Neurosci. 2016 Aug 22;8:202. doi: 10.3389/fnagi.2016.00202. eCollection 2016.
Abstract
Tendon injuries are commonly met in the emergency department. Unfortunately, tendon tissue has limited regeneration potential and usually the consequent formation of scar tissue causes inferior mechanical properties. Nanoparticles could be used in different way to improve tendon healing and regeneration, ranging from scaffolds manufacturing (increasing the strength and endurance or anti-adhesions, anti-microbial, and anti-inflammatory properties) to gene therapy. This paper aims to summarize the most relevant studies showing the potential application of nanoparticles for tendon tissue regeneration.
摘要
肌腱损伤在急诊科很常见。不幸的是，肌腱组织的再生潜力有限，通常随之形成的瘢痕组织会导致机械性能较差。纳米颗粒可通过不同方式用于改善肌腱愈合和再生，从制造支架（增强强度、耐久性或抗粘连、抗菌和抗炎特性）到基因治疗。本文旨在总结最相关的研究，展示纳米颗粒在肌腱组织再生中的潜在应用。
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