无多囊卵巢综合征患者的高催乳素血症与多毛症
Hyperprolactinemia and Hirsutism in Patients Without Polycystic Ovary Syndrome.
作者信息
Tirgar-Tabari Soudabeh, Sharbatdaran Majid, Manafi-Afkham Sara, Montazeri Mohammad
机构信息
Department of Dermatology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Department of Pathology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
出版信息
Int J Trichology. 2016 Jul-Sep;8(3):130-4. doi: 10.4103/0974-7753.188998.
BACKGROUND
Hirsutism is one of the most important diseases that lead women to refer to dermatology clinic. Hyperprolactinemia is one of the causes of hirsutism. The aim of this study was to determine prolactin (PRL) levels in hirsute women.
MATERIALS AND METHODS
In this cross-sectional study, hirsute patients were evaluated. For all of the patients, 2 or 3 days after mense starting, hormone level tests were performed, and 200 patients that had not polycystic ovary syndrome enrolled to the study. A questionnaire of history and physical examination were performed. Data have been analyzed with SPSS version 21.
RESULTS
Hyperprolactinemia were seen in 25 patients (12.5%). There was no significant relation between marital statuses, galactorrhoea, positive family history, and infertility with hyperprolactinemia. But significant relation was seen between irregular mense and hyperprolactinemia.
CONCLUSION
Although hyperprolactinemia is the rare cause of hirsutism, the prevalence of hyperprolactinemia was high in our study. Thus, PRL level in hirsute patients should be evaluate.
背景
多毛症是导致女性前往皮肤科就诊的最重要疾病之一。高泌乳素血症是多毛症的病因之一。本研究的目的是测定多毛症女性的泌乳素（PRL）水平。
材料与方法
在这项横断面研究中，对多毛症患者进行了评估。对所有患者在月经开始后2或3天进行激素水平检测，200例无多囊卵巢综合征的患者纳入研究。进行了病史问卷调查和体格检查。数据采用SPSS 21版进行分析。
结果
25例患者（12.5%）出现高泌乳素血症。婚姻状况、溢乳、家族史阳性和不孕与高泌乳素血症之间无显著相关性。但月经不规律与高泌乳素血症之间存在显著相关性。
结论
虽然高泌乳素血症是多毛症的罕见病因，但在我们的研究中高泌乳素血症的患病率较高。因此，应评估多毛症患者的PRL水平。
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