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机器人辅助全直肠系膜切除术:在直肠癌的治疗中应否被视为首选技术?

Robotic-assisted total mesorectal excision: should it be considered as the technique of choice in the management of rectal cancer?

机构信息

The Hamlyn Centre for Surgical Robotics, Institute of Global Health Innovation, Imperial College London, London, UK.

出版信息

J Robot Surg. 2012 Jun;6(2):99-114. doi: 10.1007/s11701-011-0308-1. Epub 2011 Sep 27.

DOI:10.1007/s11701-011-0308-1
PMID:27628273
Abstract

The feasibility of robotic surgery has been extensively explored over the past decade with a more recent shift towards defining focused clinical applications for which quantifiable patient benefits can be directly attributed to its use. The aim of this article is to review the current literature on the use of daVinci robotic surgery for the management of rectal cancer and identify the potential benefits, if any, that robotic-assisted total mesorectal excision (RTME) may provide over the current conventional approach. A comprehensive search strategy was used to identify relevant evidence in order to explore the oncological, operative and functional outcome measures for the RTME in addition to quantifying the level of evidence which describes the clinical effectiveness of the daVinci robot in oncological surgery. Both robotic assisted techniques and the primary outcomes are discussed. In total, 23 studies were reviewed across 11 institutions, including one pilot randomised control trial. When data repetition is disregarded, a total of 452 robotic assisted laparoscopic anterior resections and 60 robotic-assisted laparoscopic abdomino-perineal excision of the rectum have been published since the introduction of the daVinci into clinical practice. Feasibility of the daVinci robotic assisted total mesorectal excision is demonstrated, with comparable oncological outcomes presented for rectal cancer excision. A demonstration of a reduced open conversion rate as well as of reduced hospital stay with the use of the robot is highlighted, although further trials are required to confirm both these findings. No functional benefit in using the daVinci could be confirmed due to the lack of focused trials in this area.

摘要

在过去的十年中,机器人手术的可行性已经得到了广泛的探索,最近的趋势是确定其具体的临床应用,这些应用可以直接归因于机器人手术为患者带来的可量化的益处。本文旨在回顾达芬奇机器人手术在直肠癌治疗中的应用,并确定机器人辅助全直肠系膜切除术(RTME)相对于传统方法可能带来的潜在益处。采用全面的搜索策略来确定相关证据,以探讨 RTME 的肿瘤学、手术和功能结果指标,并量化描述达芬奇机器人在肿瘤手术中的临床效果的证据水平。讨论了机器人辅助技术和主要结果。总共在 11 个机构中审查了 23 项研究,包括一项试点随机对照试验。当不考虑数据重复时,自达芬奇机器人引入临床实践以来,共发表了 452 例机器人辅助腹腔镜前切除术和 60 例机器人辅助腹腔镜腹会阴直肠切除术。达芬奇机器人辅助全直肠系膜切除术的可行性得到了证实,对于直肠癌切除的肿瘤学结果也具有可比性。机器人手术的使用降低了开放转换率和住院时间,这一点得到了强调,但还需要进一步的试验来证实这两个发现。由于缺乏该领域的重点试验,因此无法确认使用达芬奇机器人是否具有功能优势。

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本文引用的文献

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Robotic vs laparoscopic resection of rectal cancer: short-term outcomes of a case-control study.机器人与腹腔镜直肠癌切除术:一项病例对照研究的短期结果。
Dis Colon Rectum. 2011 Feb;54(2):151-6. doi: 10.1007/DCR.0b013e3181fec4fd.
2
Total mesorectal excision for rectal cancer: the potential advantage of robotic assistance.直肠癌全系膜切除术:机器人辅助的潜在优势。
Dis Colon Rectum. 2010 Dec;53(12):1611-7. doi: 10.1007/DCR.0b013e3181f22f1f.
3
A new application of the four-arm standard da Vinci® surgical system: totally robotic-assisted left-sided colon or rectal resection.
四臂标准达芬奇®手术系统的新应用:全机器人辅助左半结肠或直肠切除术。
Surg Endosc. 2011 Jun;25(6):1945-52. doi: 10.1007/s00464-010-1492-1. Epub 2010 Dec 7.
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Robotic-assisted laparoscopic abdominoperineal resection for anal cancer: feasibility and technical considerations.机器人辅助腹腔镜经腹会阴直肠癌根治术治疗肛门癌:可行性和技术考虑。
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Robotic and laparoscopic total mesorectal excision for rectal cancer: a case-matched study.机器人和腹腔镜全直肠系膜切除术治疗直肠癌:一项病例匹配研究。
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Robotic-assisted versus laparoscopic surgery for low rectal cancer: case-matched analysis of short-term outcomes.机器人辅助与腹腔镜手术治疗低位直肠癌:短期结局的病例匹配分析。
Ann Surg Oncol. 2010 Dec;17(12):3195-202. doi: 10.1245/s10434-010-1162-5. Epub 2010 Jun 30.
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Robotic versus laparoscopic total mesorectal excision for rectal cancer: a comparative analysis of oncological safety and short-term outcomes.机器人与腹腔镜全直肠系膜切除术治疗直肠癌:肿瘤安全性和短期结局的对比分析。
Surg Endosc. 2010 Nov;24(11):2888-94. doi: 10.1007/s00464-010-1134-7. Epub 2010 Jun 5.
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Robotic colon and rectal surgery: a series of 131 cases.机器人结肠和直肠手术:131 例系列研究。
World J Surg. 2010 Aug;34(8):1954-8. doi: 10.1007/s00268-010-0591-4.
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Oncologic outcomes of robotic-assisted total mesorectal excision for the treatment of rectal cancer.机器人辅助全直肠系膜切除术治疗直肠癌的肿瘤学结果。
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