定制生物材料表面特性以调节宿主与植入物的相互作用：对心血管和骨治疗的意义。
Tailoring biomaterial surface properties to modulate host-implant interactions: implication in cardiovascular and bone therapy.
作者信息
Pacelli Settimio, Manoharan Vijayan, Desalvo Anna, Lomis Nikita, Jodha Kartikeya Singh, Prakash Satya, Paul Arghya
机构信息
BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA.
University of Southampton, School of Medicine, University Road, Southampton SO17 1BJ, United Kingdom.
出版信息
J Mater Chem B. 2016;4:1586-1599. doi: 10.1039/C5TB01686J. Epub 2015 Oct 16.
Abstract
Host body response to a foreign medical device plays a critical role in defining its fate post implantation. It is thus important to control host-material interactions by designing innovative implant surfaces. In the recent years, biochemical and topographical features have been explored as main target to produce this new type of bioinert or bioresponsive implants. The review discusses specific biofunctional materials and strategies to achieve a precise control over implant surface properties and presents possible solutions to develop next generation of implants, particularly in the fields of bone and cardiovascular therapy.
摘要
宿主身体对外部医疗设备的反应在决定其植入后的命运方面起着关键作用。因此，通过设计创新的植入物表面来控制宿主与材料之间的相互作用非常重要。近年来，生物化学和拓扑学特征已被探索为制造这种新型生物惰性或生物反应性植入物的主要目标。本文综述讨论了用于精确控制植入物表面特性的特定生物功能材料和策略，并提出了开发下一代植入物的可能解决方案，特别是在骨治疗和心血管治疗领域。
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J Mater Chem B. 2014 Feb 21;2(7):892-902. doi: 10.1039/c3tb21403f. Epub 2013 Dec 23.
2
Immune modulation as a therapeutic strategy in bone regeneration.免疫调节作为骨再生的一种治疗策略。
J Exp Orthop. 2015 Dec;2(1):1. doi: 10.1186/s40634-014-0017-6. Epub 2015 Feb 7.
3
Clinoenstatite coatings have high bonding strength, bioactive ion release, and osteoimmunomodulatory effects that enhance in vivo osseointegration.斜顽辉石涂层具有高结合强度、生物活性离子释放和骨免疫调节作用，能增强体内骨整合。
Biomaterials. 2015 Dec;71:35-47. doi: 10.1016/j.biomaterials.2015.08.027. Epub 2015 Aug 18.
4
Impact of surface chemistry and topography on the function of antigen presenting cells.表面化学性质和形貌对抗原提呈细胞功能的影响。
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