Furlan A, Close O N, Borhani A A, Wu Y H, Heller M T
Department of Radiology, University of Pittsburgh, UPMC Presbyterian Shadyside, Radiology, Suite 200, East Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Department of Radiology, University of Pittsburgh, UPMC Presbyterian Shadyside, Radiology, Suite 200, East Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Clin Radiol. 2017 Jan;72(1):93.e1-93.e6. doi: 10.1016/j.crad.2016.08.005. Epub 2016 Sep 12.
To perform an intra-individual comparison of the frequency of respiratory-motion artefacts on magnetic resonance imaging (MRI) in cirrhotic patients following injection of gadoxetate disodium and gadobenate dimeglumine.
Ninety-five cirrhotic patients (61 men and 34 women, mean age 58 years) underwent liver MRI with intravenous administration of gadoxetate disodium and gadobenate dimeglumine at different times (interval between studies, 189±83 days). Three readers scored the severity of respiratory-motion artefacts on the three-dimensional (3D) gradient-echo (GRE) images acquired before and after contrast medium injection. McNemar's test was used to assess the difference in frequency of new respiratory-motion artefacts and transient severe motion (TSM) artefacts between gadoxetate disodium and gadobenate dimeglumine MRI studies. The association between clinical and technical features and the occurrence of TSM on gadoxetate disodium MRI studies was investigated.
On arterial phase images, new respiratory-motion artefacts were present in 32/95 (34%) cases after injection of gadoxetate disodium, while only seen in 2/95 (2%) cases after injection of gadobenate dimeglumine (p<0.0001). TSM was present in 6/95 (6%) cases after injection of gadoxetate disodium, and in 0/95 (0%) case after injection of gadobenate dimeglumine. No clinical or technical features were associated with the occurrence of TSM.
In cirrhotic patients, respiratory-motion artefacts on arterial phase 3D GRE images are more frequently seen after injection of gadoxetate disodium than after injection of gadobenate dimeglumine.
对肝硬化患者注射钆塞酸二钠和钆贝葡胺后磁共振成像（MRI）上呼吸运动伪影的频率进行个体内比较。
95例肝硬化患者（61例男性，34例女性，平均年龄58岁）在不同时间（研究间隔为189±83天）静脉注射钆塞酸二钠和钆贝葡胺后接受肝脏MRI检查。三位阅片者对注射造影剂前后获得的三维（3D）梯度回波（GRE）图像上呼吸运动伪影的严重程度进行评分。采用McNemar检验评估钆塞酸二钠和钆贝葡胺MRI研究中新增呼吸运动伪影和短暂严重运动（TSM）伪影频率的差异。研究了临床和技术特征与钆塞酸二钠MRI研究中TSM发生之间的关联。
在动脉期图像上，注射钆塞酸二钠后32/95（34%）例出现新增呼吸运动伪影，而注射钆贝葡胺后仅2/95（2%）例出现（p<0.0001）。注射钆塞酸二钠后6/95（6%）例出现TSM，注射钆贝葡胺后0/95（0%）例出现。没有临床或技术特征与TSM的发生相关。
在肝硬化患者中，动脉期3D GRE图像上的呼吸运动伪影在注射钆塞酸二钠后比注射钆贝葡胺后更常见。
