阿尔及利亚巴特纳大学医院产OXA-48型肺炎克雷伯菌疫情，涉及序列型101克隆株
Outbreak of OXA-48-Producing Klebsiella pneumoniae Involving a Sequence Type 101 Clone in Batna University Hospital, Algeria.
作者信息
Loucif Lotfi, Kassah-Laouar Ahmed, Saidi Mahdia, Messala Amina, Chelaghma Widad, Rolain Jean-Marc
机构信息
Laboratoire de Biotechnologie des Molécules Bioactives et de la Physiopathologie Cellulaire (LBMBPC), Faculté des Sciences de la Nature et de la Vie, Université de Batna 2, Batna, Algeria.
Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes (URMITE), UM 63, CNRS 7278, IRD 198, INSERM 1095, IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Aix-Marseille-Université, Marseille, France.
出版信息
Antimicrob Agents Chemother. 2016 Nov 21;60(12):7494-7497. doi: 10.1128/AAC.00525-16. Print 2016 Dec.
Abstract
Seven nonredundant ertapenem-resistant Klebsiella pneumoniae isolates were collected between May 2014 and 19 January 2015 in the nephrology and hematology units of Batna University Hospital in Algeria. All strains coproduced the bla, bla, bla, and bla genes. Six of these isolates belonged to the pandemic clone sequence type 101 (ST101). The bla gene was located on a conjugative IncL/M-type plasmid. This is the first known outbreak of OXA-48-producing K. pneumoniae isolates involving an ST101 clone in Batna University Hospital.
摘要
2014年5月至2015年1月19日期间，在阿尔及利亚巴特纳大学医院的肾病科和血液科收集了7株无冗余的耐厄他培南肺炎克雷伯菌分离株。所有菌株均共产生bla、bla、bla和bla基因。其中6株分离株属于大流行克隆序列类型101（ST101）。bla基因位于接合性IncL/M型质粒上。这是巴特纳大学医院首次已知的涉及ST101克隆的产OXA-48肺炎克雷伯菌分离株暴发。
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