Watanabe M, Haraguchi Y
Department of Bacteriology, Kitasato Institute, Tokyo, Japan.
Antimicrob Agents Chemother. 1989 Jun;33(6):968-9. doi: 10.1128/AAC.33.6.968.
The in vitro activity of 18 antimicrobial agents against 32 strains of Bordetella parapertussis isolated from whooping cough patients was studied. The most active antimicrobial agents were piperacillin and minocycline, followed (in descending order of activity) by moxalactam, erythromycin, cefoperazone, tetracycline, ampicillin, cefotaxime, chloramphenicol, josamycin, sulfamethoxazole, and nalidixic acid. Isolates were resistant to benzylpenicillin, cephalothin, cefatrizine, cefaclor, streptomycin, and cephalexin.
研究了18种抗菌剂对从百日咳患者中分离出的32株副百日咳博德特氏菌的体外活性。活性最强的抗菌剂是哌拉西林和米诺环素，其次（按活性从高到低排序）是拉氧头孢、红霉素、头孢哌酮、四环素、氨苄西林、头孢噻肟、氯霉素、交沙霉素、磺胺甲恶唑和萘啶酸。分离株对苄青霉素、头孢噻吩、头孢曲嗪、头孢克洛、链霉素和头孢氨苄耐药。
