百日咳博德特氏菌和副百日咳博德特氏菌对24种抗生素的敏感性。
Susceptibility of Bordetella pertussis and Bordetella parapertussis to 24 antibiotics.
作者信息
Hoppe J E, Haug A, Botzenhart K
出版信息
Chemotherapy. 1987;33(4):250-4. doi: 10.1159/000238503.
The susceptibility of Bordetella pertussis (28 strains) and Bordetella parapertussis (6 strains) to 24 antibiotics (penicillin and cephalosporin derivatives, erythromycin, josamycin, cotrimoxazole, imipenem, aztreonam and fosfomycin) was studied by means of the agar dilution method using charcoal horse blood agar. Piperacillin and mezlocillin showed the highest activity (MIC 0.0039-0.00781 micrograms/ml) against B. pertussis while B. parapertussis was most susceptible to piperacillin (0.03125-0.0625 microgram/ml), mezlocillin and latamoxef (0.125-0.25 microgram/ml).
采用琼脂稀释法，以炭末马血琼脂为培养基，研究了28株百日咳博德特氏菌和6株副百日咳博德特氏菌对24种抗生素（青霉素和头孢菌素衍生物、红霉素、交沙霉素、复方新诺明、亚胺培南、氨曲南和磷霉素）的敏感性。哌拉西林和美洛西林对百日咳博德特氏菌显示出最高活性（最低抑菌浓度为0.0039 - 0.00781微克/毫升），而副百日咳博德特氏菌对哌拉西林（0.03125 - 0.0625微克/毫升）、美洛西林和拉氧头孢（0.125 - 0.25微克/毫升）最为敏感。
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