Smith D M, Mercer R R, Eldridge F L
J Appl Physiol Respir Environ Exerc Physiol. 1978 Jul;45(1):133-6. doi: 10.1152/jappl.1978.45.1.133.
We are reporting an electronic circuit which uses the peak end-tidal CO2 signal from a rapid infrared CO2 analyzer to vary the motor rate of a fixed volume respirator. It contains variable gain and a lag compensation network which permits critical damping to prevent oscillation. The CO2 analyzer, circuitry, and respirator are connected in a closed-loop servo system that allows automatic control of the CO2 level. The system's gain and performance are such that it can accommodate large changes of CO2 return to the lungs with no more than +/- 0.5 Torr carbon dioxide pressure (PCO2) error signal. It has proved useful in experiments on neural respiratory control in paralyzed animals where it is desired to keep PCO2 constant despite changes in cardiac output and venous and CO2 return to the lungs, and to monitor the approximate magnitude of these changes.
我们正在报告一种电子电路，该电路利用快速红外二氧化碳分析仪的呼气末二氧化碳峰值信号来改变定容呼吸机的马达速率。它包含可变增益和滞后补偿网络，可实现临界阻尼以防止振荡。二氧化碳分析仪、电路和呼吸机连接在一个闭环伺服系统中，该系统可自动控制二氧化碳水平。该系统的增益和性能使其能够适应二氧化碳回输到肺部的大幅变化，且二氧化碳压力（PCO2）误差信号不超过±0.5托。在瘫痪动物的神经呼吸控制实验中，该系统已证明很有用，在这些实验中，尽管心输出量以及静脉血和二氧化碳回输到肺部的情况发生变化，但仍希望保持PCO2恒定，并监测这些变化的大致幅度。
