乳腺癌中的药物乙酰化作用。
Drug acetylation in breast cancer.
作者信息
Webster D J, Flook D, Jenkins J, Hutchings A, Routledge P A
机构信息
Department of Surgery, University of Wales College of Medicine, Llandough Hospital, Penarth, South Glamorgan, UK.
出版信息
Br J Cancer. 1989 Aug;60(2):236-7. doi: 10.1038/bjc.1989.260.
Abstract
The acetylator phenotype was determined in 100 patients with breast cancer and 100 control female subjects using isoniazid. The proportion of fast acetylators in the breast cancer patients (43%) was not significantly different from the control group (43%). We conclude that acetylator phenotype is unlikely to be an important determinant of the risk of developing breast cancer.
摘要
使用异烟肼对100例乳腺癌患者和100名对照女性受试者的乙酰化代谢表型进行了测定。乳腺癌患者中快速乙酰化代谢者的比例（43%）与对照组（43%）无显著差异。我们得出结论，乙酰化代谢表型不太可能是患乳腺癌风险的重要决定因素。
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