a Department of Neurosciences, Mental Health and Sensory Organs , Suicide Prevention Centre, Sant'Andrea Hospital, Sapienza University of Rome , Rome , Italy.
b Department of Human Sciences , European University of Rome , Rome , Italy.
Int J Psychiatry Clin Pract. 2017 Sep;21(3):209-214. doi: 10.1080/13651501.2017.1301482. Epub 2017 Mar 22.
Psychiatric disorders and suicide risk (especially in psoriasis) are frequent and disabling conditions in patients with skin diseases. The aim of this study was to examine the risk of suicide and stressful life events in a sample of patients with skin disease.
A sample of 242 dermatological patients (142 women and 100 men), 112 of which had psoriasis, 77 had melanoma, and 53 were suffering with chronic allergic diseases. Patients were administered the MINI International Neuropsychiatric Interview (MINI), Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS), and the Columbia-Suicide Severity Rating Scale (C-SSRS). Patients were also asked about their experiences with stressful life events.
Patients with psoriasis were more likely to have a history of psychiatric disorders (36.6% vs. 13.2% χ = 9.55; p = 0.002) compared to patients with allergies. Specifically, patients with psoriasis more likely had a diagnosis of a mood disorder (16.1% vs. 3.9% χ = 6.85; p = 0.009; 16.1% vs. 0% χ = 9.56; p = 0.002) and reported past suicidal ideation (33.9% vs. 15.6% χ = 7.89; p = 0.005; 33.9% vs. 18.9% χ = 3.96; p = 0.047) as compared to those with melanoma and allergy.
The results from this study suggest that patients affected by psoriasis have an increased risk of psychiatric comorbidities and suicidal ideation compared to those who have other dermatological disorders.
精神障碍和自杀风险（尤其是在银屑病中）是皮肤病患者常见且致残的疾病。本研究旨在研究皮肤科患者样本中的自杀风险和压力性生活事件。
对 242 名皮肤科患者（142 名女性和 100 名男性）进行了样本调查，其中 112 名患有银屑病，77 名患有黑色素瘤，53 名患有慢性过敏性疾病。患者接受了 MINI 国际神经精神病学访谈（MINI）、汉密尔顿抑郁评定量表（HDRS）、汉密尔顿焦虑评定量表（HARS）和哥伦比亚自杀严重程度评定量表（C-SSRS）的评估。还询问了患者有关压力性生活事件的经历。
与过敏患者相比，患有银屑病的患者更有可能患有精神障碍病史（36.6%对 13.2% χ²=9.55；p=0.002）。具体而言，患有银屑病的患者更有可能被诊断为心境障碍（16.1%对 3.9% χ²=6.85；p=0.009；16.1%对 0% χ²=9.56；p=0.002）和报告过去有自杀意念（33.9%对 15.6% χ²=7.89；p=0.005；33.9%对 18.9% χ²=3.96；p=0.047）。
本研究结果表明，与患有其他皮肤病的患者相比，患有银屑病的患者更有可能出现精神共病和自杀意念。
