van der List Jelle P, Chawla Harshvardhan, Villa Jordan C, Pearle Andrew D
Computer Assisted Surgery Center, Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York.
J Arthroplasty. 2017 Mar;32(3):761-766. doi: 10.1016/j.arth.2016.08.015. Epub 2016 Aug 24.
Medial unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) are both viable treatment options for medial osteoarthritis (OA). However, it remains unclear when to choose for which arthroplasty treatment. Goals of this study were therefore to (1) compare outcomes after both treatments and (2) assess which treatment has superior outcomes in different patient subgroups.
In this retrospective cohort study, 166 patients received the RESTORIS MCK Medial UKA and 63 patients the Vanguard TKA and were radiographically matched on isolated medial OA. Western Ontario and McMaster Universities Arthritis Index scores were collected preoperatively and postoperatively (mean: 3.0 years, range: 2.0-5.0 years).
Preoperatively, no differences were observed, but medial UKA patients reported better functional outcomes than TKA (89.7 ± 13.6 vs 81.2 ± 18.0, P = .001) at follow-up.Better functional outcomes were noted after medial UKA in patients younger than age 70 years (89.5 ± 14.2 vs 78.6 ± 20.0, P = .001), with body mass index below 30 (90.3 ± 11.4 vs 83.6 ± 14.9, P = .005), with body mass index above 30 (88.3 ± 17.5 vs 78.8 ± 21.0, P = .034) and in females (90.6 ± 11.0 vs 78.1 ± 19.4, P = .001) when compared with TKA. No differences were found in males and older patients between both arthroplasties.
Superior functional outcomes were noted after medial UKA over TKA in patients presenting with medial OA with these prostheses. Subgroup analyses suggest that medial UKA is the preferred treatment in younger patients and females while no differences were noted in older patients and males after medial UKA and TKA. This might help the orthopedic surgeon in individualizing arthroplasty treatment for patients with medial OA.
内侧单髁膝关节置换术(UKA)和全膝关节置换术(TKA)都是治疗内侧骨关节炎(OA)的可行选择。然而,何时选择哪种关节置换术治疗仍不清楚。因此,本研究的目的是:(1)比较两种治疗后的结果;(2)评估哪种治疗在不同患者亚组中具有更好的结果。
在这项回顾性队列研究中,166例患者接受了RESTORIS MCK内侧UKA,63例患者接受了Vanguard TKA,并根据单纯内侧OA进行了影像学匹配。收集术前和术后(平均:3.0年,范围:2.0 - 5.0年)的西安大略和麦克马斯特大学关节炎指数评分。
术前未观察到差异,但随访时内侧UKA患者的功能结果优于TKA(89.7±13.6对81.2±18.0,P = 0.001)。与TKA相比,年龄小于70岁(89.5±14.2对78.6±20.0,P = 0.001)、体重指数低于30(90.3±11.4对83.6±14.9,P = 0.005)、体重指数高于30(88.3±17.5对78.8±21.0,P = 0.034)以及女性(90.6±11.0对78.1±19.4,P = 0.001)的患者在内侧UKA后功能结果更好。两种关节置换术在男性和老年患者中未发现差异。
使用这些假体治疗内侧OA的患者,内侧UKA后的功能结果优于TKA。亚组分析表明,内侧UKA是年轻患者和女性的首选治疗方法,而在内侧UKA和TKA后,老年患者和男性未发现差异。这可能有助于骨科医生为内侧OA患者个体化关节置换治疗。