Department of Midwifery, Students Research Committee, Faculty of Nursing and Midwifery, Tabriz University of Medical sciences, Tabriz, Iran.
Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran.
Complement Ther Med. 2019 Feb;42:95-103. doi: 10.1016/j.ctim.2018.09.015. Epub 2018 Sep 29.
BACKGROUND AND OBJECTIVE(S): Tribulus terrestris L. is an herbal plant that has long been used as sex stimulant and to treat male infertility. This systematic review collected the clinical trials and/or quasi-experimental studies on the effect of T. terrestris on sperm parameters in idiopathic male infertility.
To search the related articles, Cochrane Library, EMBASE, ProQuest, Clinicaltrial.gov, WHO, Google Scholar, MEDLINE via Pubmed, Web of Science, SID, Magiran, Irandoc, and Iranmedex databases were used without any time limitation. Words used to search were T. terrestris L., Tribestan, male infertility and sperm parameters based on the MeSH glossary. To assess the eligibility of the articles, the views of the two authors and in cases where there was no agreement, the third person was used.
Through searching of the databases, 5775 articles were identified, of which 3509 were entered after removing the duplicates. Afterward, 102 articles were screened for inclusion. Finally, 7 articles were included in this systematic review. Only one quasi-experimental without control arm article reported that the use of T. terrestris L. in the treatment of idiopathic male infertility was not effective, In the others, T. terrestris L. was reported to be effective in improving some or all parameters of the sperm, namely number, motility and morphology.
The results of the present systematic review showed that the consumption of T terrestris L., in general, resulted in the improvement of sperm parameters. This result was obtained from 6 out of the 7 articles.
蒺藜是一种草药植物，长期以来一直被用作性兴奋剂和治疗男性不育症的药物。本系统评价收集了关于蒺藜对特发性男性不育症精子参数影响的临床试验和/或准实验研究。
为了搜索相关文章，我们使用了 Cochrane Library、EMBASE、ProQuest、Clinicaltrial.gov、WHO、Google Scholar、MEDLINE 通过 Pubmed、Web of Science、SID、Magiran、Irandoc 和 Iranmedex 数据库，没有时间限制。搜索使用的词是 T. terrestris L.、Tribestan、男性不育症和精子参数，基于 MeSH 词汇表。为了评估文章的合格性，我们使用了两位作者的观点，如果存在分歧，则使用第三位作者的观点。
通过数据库搜索，共确定了 5775 篇文章，去除重复后有 3509 篇进入下一步筛选。然后，筛选了 102 篇文章以确定是否纳入。最终，有 7 篇文章纳入了本系统评价。只有一篇没有对照组的准实验性文章报告称，使用蒺藜治疗特发性男性不育症无效，而在其他文章中，蒺藜被报告为有效，可以改善精子的一些或所有参数，即数量、活力和形态。
本系统评价的结果表明，一般来说，蒺藜的摄入会改善精子参数。这一结果是从 7 篇文章中的 6 篇中得出的。
