Department of Dermatology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, NR4 7UY, U.K.
Trustee, Alopecia U.K., Shipley, U.K.
Br J Dermatol. 2017 May;176(5):1316-1320. doi: 10.1111/bjd.15099. Epub 2017 Apr 16.
Alopecia areata (AA) is a common hair loss disorder that results in patchy to complete hair loss. Many uncertainties exist around the most effective treatments for this condition.
To identify uncertainties in AA management and treatment that are important to both service users (people with hair loss, carers and relatives) and healthcare professionals.
An AA priority setting partnership was established between patients, their carers and relatives, and healthcare professionals to identify the most important uncertainties in AA. The methodology of the James Lind Alliance was followed to ensure a balanced, inclusive and transparent process.
In total, 2747 treatment uncertainties were submitted by 912 participants, of which 1012 uncertainties relating to AA (and variants) were analysed. Questions were combined into 'indicative uncertainties' following a structured format. A series of ranking exercises further reduced this list to a top 25 that were taken to a final prioritization workshop where the top 10 priorities were agreed.
We present the top 10 research priorities for AA to guide researchers and funding bodies to support studies important to both patients and clinicians.
斑秃是一种常见的脱发疾病，导致斑块状至完全脱发。对于这种情况，许多最有效的治疗方法仍然存在不确定性。
确定斑秃管理和治疗中对服务使用者（脱发者、护理人员和亲属）以及医疗保健专业人员都重要的不确定性。
在患者、护理人员和亲属以及医疗保健专业人员之间建立斑秃优先事项设定伙伴关系，以确定斑秃中最重要的不确定性。遵循詹姆斯林德联盟的方法，以确保平衡、包容和透明的过程。
共有 912 名参与者提交了 2747 项治疗不确定性，其中 1012 项与斑秃（和变体）相关的不确定性进行了分析。问题按照结构化格式组合成“指示性不确定性”。一系列排名练习进一步将该列表缩小到前 25 项，然后将这些问题带到最终的优先级确定研讨会上，会上确定了前 10 项优先级。
我们提出了斑秃的前 10 项研究重点，以指导研究人员和资助机构支持对患者和临床医生都重要的研究。
