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用于透皮给药的具有可弯曲微针阵列的自供电可穿戴粘性皮肤贴片

Toward Self-Powered Wearable Adhesive Skin Patch with Bendable Microneedle Array for Transdermal Drug Delivery.

作者信息

Wang Hao, Pastorin Giorgia, Lee Chengkuo

机构信息

Department of Electrical and Computer EngineeringNational University of Singapore4 Engineering Drive 3Singapore117576Singapore; Center for Sensors and MEMSNational University of Singapore4 Engineering Drive 3Singapore117576Singapore; Singapore Institute for Neurotechnology (SiNAPSE)National University of Singapore28 Medical Drive, #05-CORSingapore117456Singapore; NUS Suzhou Research Institute (NUSRI)Suzhou Industrial ParkSuzhou215123P. R. China.

Pharmacy Department National University of SingaporeSingapore117543Singapore; NanoCoreFaculty of EngineeringNational University of SingaporeSingapore117576Singapore; NUS Graduate School for Integrative Sciences and EngineeringCentre for Life Sciences (CeLS)Singapore117456Singapore.

出版信息

Adv Sci (Weinh). 2016 Apr 19;3(9):1500441. doi: 10.1002/advs.201500441. eCollection 2016 Sep.

Abstract

is developed with bendable microneedles, dry adhesive and triboelectric energy harvester (TEH). The bendable microneedle array can overcome the needle breakage issue. The dry adhesive can realize a conformal attachment. The TEH can generate power when attached on flat skin or joint to power active components to be integrated in the future.

摘要

它是由可弯曲微针、干粘合剂和摩擦电能量收集器(TEH)开发而成。可弯曲微针阵列能够克服针头折断问题。干粘合剂可实现贴合附着。当附着在平坦皮肤或关节上时,摩擦电能量收集器能够发电,为未来要集成的有源组件供电。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d14c/5039970/e0e5b70af730/ADVS-3-0c-g006.jpg

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