Reusch R N
Department of Microbiology and Public Health, Michigan State University, East Lansing.
Proc Soc Exp Biol Med. 1989 Sep;191(4):377-81. doi: 10.3181/00379727-191-42936.
Poly-beta-hydroxybutyrate/calcium polyphosphate (PHB-CaPolyPi) complexes exist as labile quasi-crystalline structures in bacterial plasma membranes. The composition, structure, and distribution of the complex suggest it may play a role in the regulation of intracellular calcium and in calcium signaling. The importance of these functions led to this investigation of the occurrence of PHB-CaPolyPi complexes in eukaryotes. A variety of plant and animal systems were analyzed and all were found to contain PHB associated with CaPolyPi. The intracellular location of the complex in bovine liver was primarily the mitochondria and microsomes, with smaller amounts in the plasma membranes. Eukaryotic PHB had the same narrow range of chain lengths (120-200 subunits) as PHB in bacterial membranes, and was associated with PolyPi of somewhat greater length (170-220) than the bacterial counterpart (130-170).
聚-β-羟基丁酸酯/聚磷酸钙（PHB-CaPolyPi）复合物以不稳定的准晶体结构存在于细菌质膜中。该复合物的组成、结构和分布表明它可能在细胞内钙的调节以及钙信号传导中发挥作用。这些功能的重要性促使人们对真核生物中PHB-CaPolyPi复合物的存在情况进行了此项研究。对多种动植物系统进行了分析，结果发现它们都含有与CaPolyPi相关的PHB。该复合物在牛肝中的细胞内定位主要在线粒体和微粒体中，质膜中的含量较少。真核生物的PHB具有与细菌膜中的PHB相同的狭窄链长范围（120 - 200个亚基），并且与长度略长于细菌对应物（130 - 170）的PolyPi（170 - 220）相关联。
