Dische S, Saunders M I
Br J Cancer Suppl. 1978 Jun;3:311-3.
A total of 62 patients with advanced tumours have now been treated by a fractionated course of radiotherapy, with misonidazole. The prime purpose of the administration of the drug to these patients was to determine safe dosage and suitable regimes for use in clinical radiotherapy. The reaction of normal tissues did not seem enhanced but there was an impression of increased tumour response.
共有62例晚期肿瘤患者接受了使用米索硝唑的分次放射治疗疗程。给这些患者使用该药物的主要目的是确定临床放射治疗中安全的剂量和合适的治疗方案。正常组织的反应似乎没有增强,但有肿瘤反应增加的迹象。