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慢性下腰痛患者生活质量评分与腰椎硬膜外类固醇治疗临床疗效的相关性

Correlation of quality of life scores to clinical outcome of lumbar epidural steroids in chronic low back pain.

作者信息

Singh Saru, Singh Kulvinder, Gupta Ruchi, Kaur Nayyamat, Bansal Pranav, Singh Sanjeet

机构信息

Department of Anaesthesia, BPS Government Medical College, Khanpur Kalan, Sonepat, Haryana, India.

Department of Radiology, BPS Government Medical College, Khanpur Kalan, Sonepat, Haryana, India.

出版信息

Anesth Essays Res. 2016 Sep-Dec;10(3):574-579. doi: 10.4103/0259-1162.183563.

DOI:10.4103/0259-1162.183563
PMID:27746554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5062205/
Abstract

CONTEXT AND AIM

The assessment of severity of low back pain includes subjective questionnaires to quantify the impact on routine life. The objective of current study was to correlate various quality of life (QOL) scores to the clinical outcome measured as improvement in Visual Analog Score (VAS) after interventional treatment.

SUBJECTS AND METHODS

Fifty-one consecutive chronic low backache patients were assessed for pain intensity using VAS, revised Oswestry Disability Index (ODI), Quebec's, Roland-Morris disability questionnaire (RMDQ), and depression score at presentation. All subjects received interventional therapy complemented with physiotherapy; changes in scores were evaluated at 2 weekly intervals till 12 weeks.

TYPE OF STUDY

Prospective, observational, cohort study.

RESULTS

All scores depicted highly significant statistical improvement over baseline scores ( < 0.001). The Pearson correlation of VAS with rest of the scores showed that all variables correlate well with VAS at various time periods till 3 months. However, the best outcome predictor for VAS in QOL scores was Oswestry score as well as depression score which had an additive predictive effect. Among the QOL scores best intercorrelation was found with ODI and RMDQ scores at baseline as well as at all treatment follow-ups.

INTERPRETATION AND CONCLUSION

ODI and depression score closely parallel trends of reduction in VAS indicating that these scores may be the best outcome predictor after interventional treatment of pain. Among QOL scores ODI and RMDQ evaluated in the current study record comparable degree of physical incapacity; the exception is Quebec's score.

摘要

背景与目的

下腰痛严重程度的评估包括主观问卷,以量化对日常生活的影响。本研究的目的是将各种生活质量(QOL)评分与介入治疗后以视觉模拟评分(VAS)改善来衡量的临床结果相关联。

对象与方法

连续51例慢性下背痛患者在就诊时使用VAS、修订的奥斯威斯利残疾指数(ODI)、魁北克量表、罗兰-莫里斯残疾问卷(RMDQ)以及抑郁评分评估疼痛强度。所有受试者均接受介入治疗并辅以物理治疗;每2周评估一次评分变化,直至12周。

研究类型

前瞻性观察队列研究。

结果

所有评分与基线评分相比均显示出高度显著的统计学改善(<0.001)。VAS与其他评分的Pearson相关性表明,直到3个月的各个时间段,所有变量与VAS均具有良好的相关性。然而,生活质量评分中VAS的最佳结果预测指标是奥斯威斯利评分以及抑郁评分,它们具有相加的预测作用。在生活质量评分中,基线以及所有治疗随访时,ODI与RMDQ评分之间的相互关联性最佳。

解读与结论

ODI和抑郁评分与VAS降低趋势密切平行,表明这些评分可能是疼痛介入治疗后最佳的结果预测指标。在本研究中评估的生活质量评分中,ODI和RMDQ记录的身体残疾程度相当;魁北克量表评分除外。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/7be7355fb4d4/AER-10-574-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/fcd028c3c76f/AER-10-574-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/666ecc375b02/AER-10-574-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/7be7355fb4d4/AER-10-574-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/fcd028c3c76f/AER-10-574-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/666ecc375b02/AER-10-574-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0316/5062205/7be7355fb4d4/AER-10-574-g005.jpg

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