Vadalà Maria, Morales-Medina Julio Cesar, Vallelunga Annamaria, Palmieri Beniamino, Laurino Carmen, Iannitti Tommaso
Department of General Surgery and Surgical Specialties, Surgical Clinic, University of Modena and Reggio Emilia Medical School, Modena, Italy.
Centro de Investigación en Reproducción Animal, CINVESTAV- Universidad Autónoma de Tlaxcala, Tlaxcala, Mexico.
Cancer Med. 2016 Nov;5(11):3128-3139. doi: 10.1002/cam4.861. Epub 2016 Oct 17.
Cancer is one of the most common causes of death worldwide. Available treatments are associated with numerous side effects and only a low percentage of patients achieve complete remission. Therefore, there is a strong need for new therapeutic strategies. In this regard, pulsed electromagnetic field (PEMF) therapy presents several potential advantages including non-invasiveness, safety, lack of toxicity for non-cancerous cells, and the possibility of being combined with other available therapies. Indeed, PEMF stimulation has already been used in the context of various cancer types including skin, breast, prostate, hepatocellular, lung, ovarian, pancreatic, bladder, thyroid, and colon cancer in vitro and in vivo. At present, only limited application of PEMF in cancer has been documented in humans. In this article, we review the experimental and clinical evidence of PEMF therapy discussing future perspectives in its use in oncology.
癌症是全球最常见的死因之一。现有的治疗方法伴随着众多副作用，只有低比例的患者能实现完全缓解。因此，迫切需要新的治疗策略。在这方面，脉冲电磁场（PEMF）疗法具有几个潜在优势，包括非侵入性、安全性、对非癌细胞无毒性以及可与其他现有疗法联合使用的可能性。事实上，PEMF刺激已在多种癌症类型的体外和体内研究中得到应用，这些癌症类型包括皮肤癌、乳腺癌、前列腺癌、肝细胞癌、肺癌、卵巢癌、胰腺癌、膀胱癌、甲状腺癌和结肠癌。目前，PEMF在癌症治疗中的人体应用记录有限。在本文中，我们回顾了PEMF疗法的实验和临床证据，并讨论了其在肿瘤学应用中的未来前景。
