Chia Shi Zhe Gabriel, Green Andrew, Fong Yuke Tien, Lee Haur Yueh, Ho Sweet Far
Singapore General Hospital, Singapore.
National University Health System, Singapore.
BMJ Case Rep. 2016 Oct 21;2016:bcr2016217228. doi: 10.1136/bcr-2016-217228.
Sodium hypochlorite is a clear yellowish solution with a characteristic odour of chlorine and is commonly used as a disinfectant and a bleaching agent. It is used in various healthcare settings for its fast-acting and broad-spectrum antimicrobial activity. It is a known irritant and there are some reports that it can also cause allergic contact dermatitis of type IV hypersensitivity. We report a case of work-related type I hypersensitivity to sodium hypochlorite, presenting with recurrent urticarial rash and a positive prick test reaction to this chemical. He was subsequently excused from further exposure with no further recurrences of the urticarial rash. To the best of our knowledge, this is the first such reported case due to work in the healthcare setting.
次氯酸钠是一种清澈的淡黄色溶液，具有氯气的特征气味，常用作消毒剂和漂白剂。它因其快速起效和广谱抗菌活性而被用于各种医疗环境。它是一种已知的刺激物，有一些报告称它还可引起IV型超敏反应性过敏性接触性皮炎。我们报告一例与工作相关的对次氯酸钠的I型超敏反应病例，表现为反复出现的荨麻疹皮疹以及对该化学品的点刺试验阳性反应。随后他被免除了进一步接触，荨麻疹皮疹未再复发。据我们所知，这是医疗环境中工作导致的首例此类报告病例。
