Saisho Chika, Ishii Hidenobu, Edakuni Nobutaka, Imamura Yohei, Tokito Takaaki, Kinoshita Takashi, Azuma Koichi, Yamada Kazuhiko, Hoshino Tomoaki
Division of Respirology, Neurology, and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Japan.
Intern Med. 2016;55(21):3161-3164. doi: 10.2169/internalmedicine.55.6300. Epub 2016 Nov 1.
Primary pericardial malignant mesothelioma is a very rare clinical entity and its prognosis is very poor. We herein report a 67-year-old man who presented with pericardial mesothelioma that was diagnosed 21 months after the onset of cardiac tamponade as the initial manifestation. Despite undergoing pericardiocentesis and surgical pericardial fenestration at the onset of cardiac tamponade, we were unable to make a conclusive diagnosis of mesothelioma based on the cytological and histological findings. This unusual case had a relatively long progression-free period without treatment before the appearance of pleural tumors that showed the histological features of malignant sarcomatoid mesothelioma.
原发性心包恶性间皮瘤是一种非常罕见的临床病症,其预后非常差。我们在此报告一名67岁男性,他以心包间皮瘤就诊,在心脏压塞作为初始表现出现21个月后被诊断出来。尽管在心脏压塞发作时进行了心包穿刺术和外科心包开窗术,但根据细胞学和组织学检查结果,我们仍无法对间皮瘤做出明确诊断。这个不寻常的病例在出现具有恶性肉瘤样间皮瘤组织学特征的胸膜肿瘤之前,有一段相对较长的未经治疗的无进展期。