Kivovics M, Szabó B T, Németh O, Tari N, Dőri F, Nagy P, Dobó-Nagy C, Szabó G
Department of Community Dentistry, Semmelweis University, Budapest, Hungary.
Department of Oral Diagnostics, Semmelweis University, Budapest, Hungary.
Int J Oral Maxillofac Surg. 2017 Feb;46(2):250-260. doi: 10.1016/j.ijom.2016.10.010. Epub 2016 Nov 8.
Socket preservation using a combination of porcine xenograft and collagen membrane maintains the vertical and horizontal dimensions of the ridge. The aim of this study was to evaluate the microarchitecture of the grafted area by histological analysis and micro-computed tomography. Patients in the test group (group 1; nine patients) underwent socket preservation, while the sockets in the control group (group 2; eight patients) were allowed to heal without preservation. After a 6-month healing period, bone core biopsy samples were obtained and implants were placed in the augmented sites in the test group (12 biopsy samples) and the non-augmented sockets of the control group (12 biopsy samples). Analysis of the biopsy samples obtained from group 1 revealed that particles of the graft were surrounded by newly formed bone in eight cases and by granulation tissue in four cases. Micromorphometric data showed statistically significant differences in several parameters between the microarchitecture of the native bone and the newly formed bone within the augmented sites, which suggests that the xenograft particles interfere with the bony healing of the alveoli.
使用猪异种移植物和胶原膜联合进行牙槽窝保存可维持牙槽嵴的垂直和水平尺寸。本研究的目的是通过组织学分析和微型计算机断层扫描评估移植区域的微观结构。试验组（第1组；9例患者）进行牙槽窝保存，而对照组（第2组；8例患者）的牙槽窝不进行保存任其愈合。经过6个月的愈合期后，获取骨芯活检样本，并在试验组的增量部位（12个活检样本）和对照组的未增量牙槽窝（12个活检样本）植入种植体。对从第1组获得的活检样本分析显示，8例移植颗粒被新形成的骨包围，4例被肉芽组织包围。微观形态测量数据显示，增量部位的天然骨和新形成骨的微观结构在几个参数上存在统计学显著差异，这表明异种移植颗粒干扰了牙槽骨的愈合。
