HLA - B27阳性和阴性关节炎患者的多形核白细胞化学发光反应
Polymorphonuclear leukocyte chemiluminescence response in HLA-B27 positive and negative arthritic patients.
作者信息
Tertti R
机构信息
Department of Medical Microbiology, University of Turku, Finland.
出版信息
Rheumatol Int. 1989;8(6):279-82. doi: 10.1007/BF00270985.
The polymorphonuclear leukocyte (PMN) chemiluminescence (CL) response to opsonized zymosan reflecting the C3b/C3bi-receptor-mediated PMN respiratory burst activation was studied in 99 arthritic patients typed for the HLA-B27 antigen. The results indicate that the B27 antigen per se is not associated with disturbances in PMN CL response. However, the erythrocyte sedimentation rate showed a correlation with CL, suggesting that the activity of arthritic disease may affect the PMN CL response.
在99名已进行HLA - B27抗原分型的关节炎患者中，研究了多形核白细胞（PMN）对调理酵母聚糖的化学发光（CL）反应，该反应反映了C3b/C3bi受体介导的PMN呼吸爆发激活。结果表明，B27抗原本身与PMN CL反应紊乱无关。然而，红细胞沉降率与CL相关，提示关节炎疾病的活动可能影响PMN CL反应。
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