Henneberger P K, Ferris B G, Monson R R
Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts 02115.
Br J Ind Med. 1989 Sep;46(9):658-64. doi: 10.1136/oem.46.9.658.
Cause specific mortality was analysed among 883 white male workers from a paper company in Berlin, New Hampshire. Subjects were assigned to different exposure groups on the basis of their having worked in the pulp mill, the paper mill, or elsewhere in the paper company. A standardised mortality ratio (SMR) analysis was used to compare death rates for each of the exposure groups with United States national rates. For all the subjects, deaths due to all causes, all malignant neoplasms, and lung cancer were close to the number expected and excesses were noted for cancers of the digestive system and leukaemia. Among pulp mill workers, the number of cancers of the digestive system was raised and the SMR for pancreatic cancer was especially high (SMR = 305, 95% CI = 98-712). Among paper mill workers, more deaths were due to leukaemia and cancers of the digestive system than expected. These results are consistent with the findings from other studies that employment in pulp and paper mills is associated with excess mortality due to digestive and lymphopoietic cancers.
对新罕布什尔州柏林一家造纸公司的883名白人男性工人进行了死因特异性死亡率分析。根据他们是在纸浆厂、造纸厂还是造纸公司的其他地方工作,将研究对象分配到不同的暴露组。采用标准化死亡率比(SMR)分析,将每个暴露组的死亡率与美国全国死亡率进行比较。对于所有研究对象,所有原因、所有恶性肿瘤和肺癌导致的死亡人数接近预期,消化系统癌症和白血病的死亡人数则超过预期。在纸浆厂工人中,消化系统癌症的数量有所增加,胰腺癌的标准化死亡率尤其高(SMR = 305,95%可信区间 = 98 - 712)。在造纸厂工人中,白血病和消化系统癌症导致的死亡人数比预期更多。这些结果与其他研究的发现一致,即在纸浆厂和造纸厂工作与因消化系统和淋巴造血系统癌症导致的超额死亡率有关。