Meloni-Balliet A, Morgan R, Poth J L, Kingsley E C, Sandberg A A
Genetics Center of Southwest Biomedical Research Center, Scottsdale, AZ 85251.
Cancer Genet Cytogenet. 1989 Nov;43(1):35-8. doi: 10.1016/0165-4608(89)90124-6.
Three cases of acute nonlymphocytic leukemia with trisomy 14 as the sole chromosome abnormality are presented and it is suggested that this type of trisomy, either as an extra chromosome or an isochromosome, is phenotypically equivalent. The findings are presented in relation to other cases previously reported.
本文报告了3例以14号染色体三体作为唯一染色体异常的急性非淋巴细胞白血病病例,并指出这种三体类型,无论是额外染色体还是等臂染色体,在表型上是等效的。文中还结合先前报道的其他病例展示了相关研究结果。