Amundsen M S, Kirkeby T M G, Giri S, Koju R, Krishna S S, Ystgaard B, Solligård E, Risnes K
Norwegian University of Science and Technology, NTNU, P.O. Box No.: 7491, Trondheim, Norway; St. Olavs Hospital, Children's Clinic, Olav Kyrres Gate 11, P.O. Box 7030, Trondheim, Norway.
Norwegian University of Science and Technology, NTNU, P.O. Box No.: 7491, Trondheim, Norway; St. Olavs Hospital, Clinic of Emergency Medicine and Prehospital Care, Prinsesse Kristinas Gate 3, P.O. Box. No: 7030, Trondheim, Norway.
Alcohol. 2016 Dec;57:9-14. doi: 10.1016/j.alcohol.2016.10.008. Epub 2016 Oct 20.
Recent global burden of disease reports find that a major proportion of global deaths and disability worldwide can be attributed to alcohol use. Thus, it may be surprising that very few studies have reported on the burden of alcohol-related disease in low income settings. The evidence of non-communicable disease (NCD) burden in Nepal was recently reviewed and concluded that data is still lacking, particularly to describe the burden of alcohol-related diseases (ARDs). Therefore, here we report on NCD burden and specifically ARDs, in hospitalized patients at a regional hospital in Nepal. We conducted a retrospective chart-review that included detailed information on all discharged patients during a four month period. A local database that included sociodemographic information and diagnoses at discharge was established. All doctor-assigned discharge diagnoses were retrospectively assigned ICD-10 codes. A total of 1,139 hospitalized adult patients were included in the study and one third of these were NCDs (n = 332). The main NCDs were chronic obstructive pulmonary disease (COPD) (n = 148, 45%) and ARDs (n = 57, 17%). Patients with ARD often presented with signs of liver cirrhosis and were typically younger men, with a median age at 43 years, from specific ethnic groups. These data demonstrate that severe alcohol-related organ failure in relatively young men contributed to a high proportion of NCDs in a regional hospital in Nepal. These findings are novel and alarming and warrant further studies that can establish the burden of ARDs and alcohol use in Nepal and other similar low-income countries.
近期的全球疾病负担报告发现，全球范围内很大一部分死亡和残疾可归因于饮酒。因此，很少有研究报道低收入地区与酒精相关疾病的负担，这可能令人惊讶。最近对尼泊尔非传染性疾病（NCD）负担的证据进行了审查，得出的数据仍然缺乏，特别是关于酒精相关疾病（ARDs）负担的描述。因此，我们在此报告尼泊尔一家地区医院住院患者的非传染性疾病负担，特别是酒精相关疾病负担。我们进行了一项回顾性病历审查，其中包括四个月期间所有出院患者的详细信息。建立了一个包含社会人口统计学信息和出院诊断的本地数据库。所有医生指定的出院诊断都被追溯分配了ICD - 10编码。共有1139名住院成年患者纳入研究，其中三分之一为非传染性疾病（n = 332）。主要的非传染性疾病是慢性阻塞性肺疾病（COPD）（n = 148，45%）和酒精相关疾病（n = 57，17%）。酒精相关疾病患者通常表现出肝硬化迹象，且通常为较年轻男性，中位年龄为43岁，来自特定种族群体。这些数据表明，相对年轻男性中严重的酒精相关器官衰竭在尼泊尔一家地区医院的非传染性疾病中占了很大比例。这些发现是新颖且令人担忧的，需要进一步研究以确定尼泊尔及其他类似低收入国家酒精相关疾病和饮酒的负担。
