Sulotto F, Romano C, Piolatto G, Chiesa A, Capellaro E, Discalzi G
Med Lav. 1989 May-Jun;80(3):201-10.
A group of 68 currently employed welders were examined who were exposed to welding fumes either for the whole or for at least half the working day and who used at least two welding processes, which were mainly manual metal arc welding and metal active gas welding, but also metal and tungsten inert gas welding, or oxyacetylene welding. The welders were classified into 3 groups according to the class of materials used, i.e.: 1) only mild and stainless steel; 2) mild and stainless steel and other metals; 3) only other metals. Chronic bronchitis symptoms were observed in 22% of the subjects; signs of suspected radiological fibrosis were present in 18%, initial signs of radiological fibrosis in 4%. Small airway disease was prevalent in the smokers (28 smokers versus 2 nonsmokers); one worker had an obstructive syndrome and another a restrictive syndrome (both were smokers). There was a good correlation between years of exposure and: 1) MEF25 in non-smokers; 2) urinary cobalt in the whole group. There was also a correlation between smoking and FEV1, MEF50, MEF25, PaO2 and urinary cadmium. Serum copper was higher in workers exposed full time than in those exposed part time. Urinary chromium and cobalt and serum copper were high in steel welders, lower in welders using steel and other metals and low in welders using other metals. Urinary chromium was similar in smokers and non-smokers. Serum zinc was found to be of little use for biological monitoring of welders. Urinary chromium was studied for one week in 10 full-time exposed steel welders. The difference between the chromium values at the end of the workshift and those at the beginning was small (low current exposure); the chromium values at the end of the workshift were not uniform in the whole group (different past exposure levels).
对一组68名在职焊工进行了检查,他们要么全天接触焊接烟雾,要么至少在工作日的一半时间接触焊接烟雾,且使用至少两种焊接工艺,主要是手工金属电弧焊和活性气体保护焊,也包括熔化极惰性气体保护焊、钨极惰性气体保护焊或氧乙炔焊。根据所使用材料的类别,将焊工分为3组,即:1)仅使用低碳钢和不锈钢;2)低碳钢、不锈钢及其他金属;3)仅使用其他金属。22%的受试者出现慢性支气管炎症状;18%有疑似放射性纤维化迹象,4%有放射性纤维化初期迹象。小气道疾病在吸烟者中很普遍(28名吸烟者对2名不吸烟者);一名工人患有阻塞性综合征,另一名患有限制性综合征(两人均为吸烟者)。接触年限与以下因素之间存在良好相关性:1)非吸烟者的最大呼气中期流速25%(MEF25);2)全组的尿钴含量。吸烟与第一秒用力呼气容积(FEV1)、最大呼气中期流速50%(MEF50)、MEF25、动脉血氧分压(PaO2)和尿镉之间也存在相关性。全职接触的工人血清铜含量高于兼职接触的工人。钢焊工的尿铬、尿钴和血清铜含量较高,使用钢和其他金属的焊工含量较低,使用其他金属的焊工含量最低。吸烟者和非吸烟者的尿铬含量相似。发现血清锌对焊工的生物监测作用不大。对10名全职接触的钢焊工的尿铬进行了为期一周的研究。工作班次结束时的铬值与开始时的铬值差异很小(当前接触量低);全组工作班次结束时的铬值不一致(过去接触水平不同)。