Mercelina L F, Degenaar C P, Nieuwenhuijzen Kruseman A C
Ned Tijdschr Geneeskd. 1989 Sep 23;133(38):1887-90.
The predictive values of fasting blood glucose and serum fructosamine for monitoring long-term diabetic control were investigated in 98 non-insulin dependent diabetic patients. The HbAlc percentage was taken as standard in this study. Despite a significant correlation, the predictive values of the parameters studied for an acceptable HbAlc-value appeared to be low (37% and 44% respectively), possibly due to differences in periods of time in which these parameters can change during variable metabolic control. In addition, the serum fructosamine value may vary due to variations in serum albumin and lipid content. It is concluded that the fasting blood glucose and serum fructosamine values cannot replace HbAlc measurement for monitoring diabetic control, but are supplementary for assessment of this control over short- and long-term periods of time.
对98例非胰岛素依赖型糖尿病患者进行了空腹血糖和血清果糖胺监测长期糖尿病控制情况的预测价值研究。本研究以糖化血红蛋白(HbAlc)百分比作为标准。尽管存在显著相关性,但所研究参数对于可接受的HbAlc值的预测价值似乎较低(分别为37%和44%),这可能是由于在代谢控制变化期间这些参数发生变化的时间段不同所致。此外,血清果糖胺值可能因血清白蛋白和脂质含量的变化而有所不同。得出的结论是,空腹血糖和血清果糖胺值不能替代糖化血红蛋白测量来监测糖尿病控制情况,但在短期和长期评估这种控制情况时具有补充作用。