Elvira Partida L, Fernández M, Gutiérrez J, Esnal A, Benavides J, Pérez V, de la Torre A, Álvarez M, Esperón F
MSD Animal Health, Salamanca, Spain.
Animal Health Department, Instituto de Ganadería de Montaña (CSIC-ULE), University of León, León, Spain.
Transbound Emerg Dis. 2017 Feb;64(1):19-26. doi: 10.1111/tbed.12599. Epub 2016 Dec 21.
Outbreaks of abortions and lambs born with nervous clinical signs and/or congenital malformations affected different sheep farms in Spain. Initial diagnosis of 'border disease-like' was established, based on clinical signs, serology and/or RNA detection by a pan-pestivirus RT-PCR. However, further investigation using immunohistochemical and molecular techniques identified BVDV-2b as the aetiological agent.
流产疫情以及出生时伴有神经临床症状和/或先天性畸形的羔羊疫情影响了西班牙的不同养羊场。基于临床症状、血清学检测和/或通过泛瘟病毒逆转录聚合酶链式反应（RT-PCR）进行的RNA检测，初步诊断为“类边境病”。然而，通过免疫组织化学和分子技术进行的进一步调查确定牛病毒性腹泻病毒2b型（BVDV-2b）为病原体。
