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多重单细胞成像:过去、现在与未来

Multiplexed Single-Cell Imaging: Past, Present, and Future.

作者信息

Lin Jia-Ren

机构信息

Laboratory of Systems Pharmacology, HMS LINCS Center , Harvard Medical School Boston, Boston, Massachusetts.

出版信息

Assay Drug Dev Technol. 2017 Jan;15(1):8-10. doi: 10.1089/adt.2016.765. Epub 2016 Dec 22.

Abstract

Jia-Ren Lin from the Laboratory of Systems Pharmacology at Harvard Medical School was awarded best poster at the annual Society of Biomolecular Imaging and Informatics meeting held in Boston, September 2016. His work focuses on single-cell imaging, especially on developing new methods for simultaneously detecting many antigens, named cyclic immunofluorescence (CycIF). This method could be applied in different stages of drug development, from discovery phase, preclinical research to clinical research. The current works and future directions of CycIF method are summarized in the following overview.

摘要

来自哈佛医学院系统药理学实验室的林家仁在2016年9月于波士顿举行的年度生物分子成像与信息学会会议上荣获最佳海报奖。他的工作专注于单细胞成像,尤其致力于开发同时检测多种抗原的新方法,即循环免疫荧光法(CycIF)。该方法可应用于药物研发的不同阶段,从发现阶段、临床前研究到临床研究。以下概述总结了CycIF方法的当前工作及未来方向。

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