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青光眼和高眼压症中视觉诱发电位(VEP)与视野指数(Octopus G1)的相关性

The correlation of visual evoked potentials (VEP) and visual field indices (Octopus G1) in glaucoma and ocular hypertension.

作者信息

Nykänen H, Raitta C

机构信息

Department of Ophthalmology, University of Helsinki, Finland.

出版信息

Acta Ophthalmol (Copenh). 1989 Aug;67(4):393-5. doi: 10.1111/j.1755-3768.1989.tb01621.x.

DOI:10.1111/j.1755-3768.1989.tb01621.x
PMID:2801040
Abstract

Flash evoked responses and the visual field indices (VFI) of the Octopus G1 program were recorded from 42 eyes of 21 patients, aged 23-76 years (mean 51 years); 29 eyes had open-angle glaucoma (OAG) and 10 ocular hypertension (OH). Three eyes were normal. The early component of the VEP called P 120 had lower amplitude in glaucomatous eyes compared with normal or hypertensive eyes. Mean sensitivity (MS), mean defect (MD), and short time fluctuation (SF), indicative of diffuse non-specific nerve fiber los, correlated significantly (P less than 0.05). Reliability factor (RF), which is indicative of psychodynamic factors, also correlated significantly (P less than 0.05) in eyes with OAG.

摘要

对21例年龄在23 - 76岁(平均51岁)患者的42只眼睛记录了闪光诱发反应和Octopus G1程序的视野指数(VFI);其中29只眼睛患有开角型青光眼(OAG),10只眼睛患有高眼压症(OH)。3只眼睛正常。与正常或高血压眼睛相比,青光眼眼睛中视觉诱发电位(VEP)的早期成分P120振幅较低。提示弥漫性非特异性神经纤维丢失的平均敏感度(MS)、平均缺损(MD)和短时间波动(SF)显著相关(P < 0.05)。提示心理动力学因素的可靠性因子(RF)在OAG患者的眼睛中也显著相关(P < 0.05)。

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Neurosci J. 2013;2013:418320. doi: 10.1155/2013/418320. Epub 2012 Dec 6.
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J Ophthalmol. 2013;2013:908017. doi: 10.1155/2013/908017. Epub 2013 May 7.