Medical Practices Evaluation Center, Massachusetts General Hospital and Harvard Medical School, Center for Survey Research, University of Massachusetts, Boston, Massachusetts; Department of Urology, Tufts University School of Medicine, Boston, Massachusetts; Department of Urology, University of Wisconsin at Madison, Madison, Wisconsin; Department of Urology, Johns Hopkins University, Baltimore, Maryland; Department of Urology, University of Rochester Medical Center, Rochester, New York; Section of Urology, The University of Kansas Medical Center, Kansas City, Kansas, and the American Urological Association.
J Urol. 2017 Feb;197(2S):S189-S197. doi: 10.1016/j.juro.2016.10.071. Epub 2016 Dec 22.
A symptom index for benign prostatic hyperplasia (BPH) was developed and validated by a multidisciplinary measurement committee of the American Urological Association (AUA). Validation studies were conducted involving a total of 210 BPH patients and 108 control subjects. The final AUA symptom index includes 7 questions covering frequency, nocturia, weak urinary stream, hesitancy, intermittence, incomplete emptying and urgency. On revalidation, the index was internally consistent (Cronbach's α = 0.86) and the score generated had excellent test-retest reliability (r = 0.92). Scores were highly correlated with subjects' global ratings of the magnitude of their urinary problem (r = 0.65 to 0.72) and powerfully discriminated between BPH and control subjects (receiver operating characteristic area 0.85). Finally, the index was sensitive to change, with preoperative scores decreasing from a mean of 17.6 to 7.1 by 4 weeks after prostatectomy (p <0.001). The AUA symptom index is clinically sensible, reliable, valid and responsive. It is practical for use in practice and for inclusion in research protocols.
良性前列腺增生症（BPH）症状指数由美国泌尿协会（AUA）的多学科测量委员会制定和验证。验证研究共涉及 210 名 BPH 患者和 108 名对照受试者。最终的 AUA 症状指数包括 7 个问题，涵盖频率、夜尿、尿流弱、犹豫、间歇性、不完全排空和紧迫性。在重新验证时，该指数具有内部一致性（Cronbach's α = 0.86），生成的评分具有极好的重测信度（r = 0.92）。评分与受试者对其尿问题严重程度的总体评价高度相关（r = 0.65 至 0.72），并有力地区分了 BPH 和对照组（受试者工作特征曲线下面积为 0.85）。最后，该指数对变化敏感，前列腺切除术后 4 周，术前评分从平均 17.6 分降至 7.1 分（p <0.001）。AUA 症状指数具有临床意义、可靠性、有效性和响应性。它在实践中实用，也适用于研究方案。
