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芍药花中黄酮类化合物的抗氧化活性及化学成分

Antioxidant Activities and Chemical Constituents of Flavonoids from the Flower of Paeonia ostii.

作者信息

Zhang Huifang, Li Xiaofang, Wu Ke, Wang Mengke, Liu Pu, Wang Xinsheng, Deng Ruixue

机构信息

Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Luoyang 471023, Henan, China.

出版信息

Molecules. 2016 Dec 23;22(1):5. doi: 10.3390/molecules22010005.

Abstract

is a traditional medicinal plant popularly used in China. This study intended to evaluate the antioxidant properties and the chemical components of the flavonoid-rich extracts from the flowers of . The results showed that the flavonoid-rich extracts from the flowers of had strong scavenging capacities on 2,2'-Azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS), hydroxyls, superoxide anions, and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals in a dose-dependent manner. Five flavonoids, dihydrokaempferol (), apigenin-7--β-d-glucoside (), apigenin-7--β-d-neohesperidoside (), kaempferol-7--β-d-glucopyranoside (), and kaempferol-3--β-d-glucopyranosyl-7--β-d-glucopyranoside (), were isolated from the flavonoid-rich extracts of the flowers of . High-performance liquid chromatography (HPLC) analysis revealed that compounds and were abundant in the flower and in flavonoid-rich extracts. The main components of the flower of are flavonoids. The high antioxidant activity of the flavonoid-rich extracts may be attributed to the high content of flavonoids. The five isolated flavonoids were the primary antioxidant ingredients, and may play important roles in the strong antioxidant activities of this flower. Based on the obtained results, the flower of could be a potential source of natural antioxidants in food and pharmaceutical applications.

摘要

是一种在中国广泛使用的传统药用植物。本研究旨在评估[植物名称]花中富含黄酮类化合物提取物的抗氧化性能和化学成分。结果表明,[植物名称]花中富含黄酮类化合物的提取物对2,2'-联氮双(3-乙基苯并噻唑啉-6-磺酸)(ABTS)、羟基、超氧阴离子和1,1-二苯基-2-苦基肼(DPPH)自由基具有强清除能力,且呈剂量依赖性。从[植物名称]花中富含黄酮类化合物的提取物中分离出了五种黄酮类化合物,分别为二氢山奈酚()、芹菜素-7--β -D-葡萄糖苷()、芹菜素-7--β -D-新橙皮糖苷()、山奈酚-7--β -D-葡萄糖吡喃糖苷()和山奈酚-3--β -D-吡喃葡萄糖基-7--β -D-吡喃葡萄糖苷()。高效液相色谱(HPLC)分析表明,化合物[具体化合物名称]和[具体化合物名称]在[植物名称]花及其富含黄酮类化合物的提取物中含量丰富。[植物名称]花的主要成分是黄酮类化合物。富含黄酮类化合物的提取物具有高抗氧化活性可能归因于黄酮类化合物的高含量。分离出的五种黄酮类化合物是主要的抗氧化成分,可能在该花的强抗氧化活性中发挥重要作用。基于所得结果,[植物名称]花可能是食品和制药应用中天然抗氧化剂的潜在来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec22/6155618/a142da28e341/molecules-22-00005-g001.jpg

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