Triterpenoid Saponins and Flavonoid Glycosides from the Flower of and Their Cytotoxic and α-Glycosidase Inhibitory Activities.

var. flavida, commonly known as "Jinhua Tea", has its flowers and leaves traditionally utilized as tea and functional food sources. However, there is limited knowledge about its bioactive components and their biological activities. This study isolated ten previously unidentified glycoside compounds from the flowers of , including three oleanane-type triterpenoid saponins (compounds -) and seven flavonoid glycosides (compounds -), collectively named flavidosides A-J. This study assessed the cytotoxicity of these compounds against a panel of human cancer cell lines and their α-glucosidase inhibitory activities. Notably, flavidoside C showed significant cytotoxicity against BEL-7402 and MCF-7 cell lines, with IC values of 4.94 ± 0.41 and 1.65 ± 0.39 μM, respectively. Flavidoside H exhibited potent α-glucosidase inhibitory activity, with an IC value of 1.17 ± 0.30 mM. These findings underscore the potential of in the development of functional foods.