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ABO 血型与老年人群骨质疏松和骨量减少症的患病率:基于阿莫尔科拉健康与老龄化项目(AHAP)的研究。

ABO Blood Group and Prevalence of Osteoporosis and Osteopenia in the Elderly Population: An Amirkola Health and Ageing Project (AHAP)-Based Study.

机构信息

Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

J Clin Densitom. 2018 Apr-Jun;21(2):200-204. doi: 10.1016/j.jocd.2016.10.006. Epub 2016 Dec 26.

DOI:10.1016/j.jocd.2016.10.006
PMID:28034588
Abstract

Osteoporosis is known as a degenerative disease of the skeletal system and its main complication is fracture, which influences quality of life in the elderly. There are 4 major blood groups in humans based on the presence of A and B antigens. According to the investigations, there are reported relations between blood types and some diseases. In this study, the association between the ABO blood group and the prevalence of osteoporosis and osteopenia in an elderly population was investigated. Medical records of 990 elderly people were investigated in a cross-sectional study and the association between their blood group and the incidence of osteoporosis and osteopenia was analyzed using SPSS version 17.0 (SPSS Inc., Chicago, IL, USA). The results showed that ABO blood groups had no association with the prevalence of osteoporosis in both elderly men and women. The association between age and osteoporosis was significant and the association between this disorder and gender was significant too. The results also indicate that there is no association between RH and RH blood types and osteoporosis and osteopenia in both men and women. Based on this finding, it would be reasonable to conduct extensive studies.

摘要

骨质疏松症是一种骨骼系统的退行性疾病,其主要并发症是骨折,这会影响老年人的生活质量。人类有 4 种主要血型,根据 A 和 B 抗原的存在情况而定。根据调查,有报道称血型与某些疾病之间存在关系。在这项研究中,调查了 ABO 血型与老年人群骨质疏松症和骨量减少的患病率之间的关系。在一项横断面研究中调查了 990 名老年人的病历,并使用 SPSS 版本 17.0(SPSS Inc.,芝加哥,IL,美国)分析了他们的血型与骨质疏松症和骨量减少发生率之间的关系。结果表明,ABO 血型与男女骨质疏松症的患病率无关。年龄与骨质疏松症之间存在显著关联,这种疾病与性别之间也存在显著关联。结果还表明,男女的 RH 和 RH 血型与骨质疏松症和骨量减少之间没有关联。基于这一发现,进行广泛的研究是合理的。

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J Orthop Surg Res. 2021 Oct 17;16(1):609. doi: 10.1186/s13018-021-02772-0.
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Cohort Profile Update: The Amirkola Health and Ageing Project (AHAP).队列简介更新:阿米科拉健康与老龄化项目(AHAP)。
Caspian J Intern Med. 2017 Summer;8(3):205-212. doi: 10.22088/cjim.8.3.205.