Neiva Rodrigo F, Gil Luiz Fernando, Tovar Nick, Janal Malvin N, Marao Heloisa Fonseca, Bonfante Estevam Augusto, Pinto Nelson, Coelho Paulo G
Department of Periodontology, University of Florida, 1395 Center Drive, D1-11, Gainesville, FL 32610, USA.
Department of Dentistry, Universidade Federal de Santa Catarina, R. Eng. Agronômico Andrei Cristian Ferreira, s/n Trindade, 88040-900 Florianópolis, SC, Brazil.
Biomed Res Int. 2016;2016:9507342. doi: 10.1155/2016/9507342. Epub 2016 Nov 30.
. This study evaluated the effects of L-PRF presence and implant surface texture on bone healing around immediately placed implants. . The first mandibular molars of 8 beagle dogs were bilaterally extracted, and implants (Blossom™, Intra-Lock International, Boca Raton, FL) were placed in the mesial or distal extraction sockets in an interpolated fashion per animal. Two implant surfaces were distributed per sockets: (1) dual acid-etched (DAE, micrometer scale textured) and (2) micrometer/nanometer scale textured (Ossean™ surface). L-PRF (Intraspin system, Intra-Lock International) was placed in a split-mouth design to fill the macrogap between implant and socket walls on one side of the mandible. The contralateral side received implants without L-PRF. A mixed-model ANOVA (at = 0.05) evaluated the effect of implant surface, presence of L-PRF, and socket position (mesial or distal), individually or in combination on bone area fraction occupancy (BAFO). . BAFO values were significantly higher for the Ossean relative to the DAE surface on the larger mesial socket. The presence of L-PRF resulted in higher BAFO. The Ossean surface and L-PRF presence resulted in significantly higher BAFO. L-PRF and the micro-/nanometer scale textured surface resulted in increased bone formation around immediately placed implants.
本研究评估了富血小板纤维蛋白（L-PRF）的存在以及种植体表面纹理对即刻种植体周围骨愈合的影响。选取8只比格犬，双侧拔除其第一下颌磨牙，每只动物以插入方式在近中或远中拔牙窝植入种植体（Blossom™，Intra-Lock International，博卡拉顿，佛罗里达州）。每个拔牙窝分布两种种植体表面：（1）双重酸蚀（DAE，微米级纹理）和（2）微米/纳米级纹理（Ossean™表面）。采用分口设计放置富血小板纤维蛋白（Intraspin系统，Intra-Lock International），以填充下颌骨一侧种植体与牙槽窝壁之间的宏观间隙。对侧植入未放置富血小板纤维蛋白的种植体。采用混合模型方差分析（α = 0.05）评估种植体表面、富血小板纤维蛋白的存在以及牙槽窝位置（近中或远中）单独或联合对骨面积分数占有率（BAFO）的影响。在较大的近中牙槽窝中，相对于DAE表面，Ossean表面的BAFO值显著更高。富血小板纤维蛋白的存在导致BAFO更高。Ossean表面和富血小板纤维蛋白的存在导致BAFO显著更高。富血小板纤维蛋白和微米/纳米级纹理表面导致即刻种植体周围骨形成增加。
