扁平苔藓中的代谢紊乱——一项病例对照研究
Metabolic Derangements in Lichen Planus - A Case Control Study.
作者信息
Kar Bikash Ranjan, Panda Maitreyee, Patro Nibedita
机构信息
Professor, Department of Skin and VD, IMS and SUM Hospital , Bhubaneswar, Odisha, India .
Assistant Professor, Department of Skin and VD, All India Institute of Medical Sciences (AIIMS) , Bhubaneswar, Odisha, India .
出版信息
J Clin Diagn Res. 2016 Nov;10(11):WC01-WC03. doi: 10.7860/JCDR/2016/21993.8818. Epub 2016 Nov 1.
INTRODUCTION
An association between psoriasis and metabolic syndrome has been established in previous studies. Lichen Planus (LP) is also a chronic inflammatory disease morphologically related to psoriasis and few studies have shown association of metabolic derangements in LP.
AIM
To study the association of metabolic derangements in LP.
MATERIALS AND METHODS
A prospective case control study was undertaken for a period of one year. Age and sex matched patients of LP and other non-inflammatory diseases were taken as cases and controls respectively. Data on height, weight, lipid profile and fasting blood glucose levels were collected for all the patients. Body Mass Index (BMI) was calculated.
RESULTS
A total of 80 patients were recruited, 40 cases and 40 controls. The mean values for all the lipid and glucose parameters were high in cases as compared to controls with significant p-values.
CONCLUSION
In the present study metabolic derangements were seen in patients with LP.
引言
先前的研究已证实银屑病与代谢综合征之间存在关联。扁平苔藓（LP）也是一种与银屑病在形态学上相关的慢性炎症性疾病，少数研究表明LP存在代谢紊乱的关联。
目的
研究LP中代谢紊乱的关联。
材料与方法
进行了为期一年的前瞻性病例对照研究。将年龄和性别匹配的LP患者和其他非炎症性疾病患者分别作为病例组和对照组。收集了所有患者的身高、体重、血脂谱和空腹血糖水平数据。计算了体重指数（BMI）。
结果
共招募了80名患者，40例病例和40例对照。与对照组相比，病例组所有脂质和血糖参数的平均值均较高，p值具有显著性。
结论
在本研究中，LP患者出现了代谢紊乱。
Zotero 插件