• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

扁平苔藓中的代谢紊乱——一项病例对照研究

Metabolic Derangements in Lichen Planus - A Case Control Study.

作者信息

Kar Bikash Ranjan, Panda Maitreyee, Patro Nibedita

机构信息

Professor, Department of Skin and VD, IMS and SUM Hospital , Bhubaneswar, Odisha, India .

Assistant Professor, Department of Skin and VD, All India Institute of Medical Sciences (AIIMS) , Bhubaneswar, Odisha, India .

出版信息

J Clin Diagn Res. 2016 Nov;10(11):WC01-WC03. doi: 10.7860/JCDR/2016/21993.8818. Epub 2016 Nov 1.

DOI:10.7860/JCDR/2016/21993.8818
PMID:28050485
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5198438/
Abstract

INTRODUCTION

An association between psoriasis and metabolic syndrome has been established in previous studies. Lichen Planus (LP) is also a chronic inflammatory disease morphologically related to psoriasis and few studies have shown association of metabolic derangements in LP.

AIM

To study the association of metabolic derangements in LP.

MATERIALS AND METHODS

A prospective case control study was undertaken for a period of one year. Age and sex matched patients of LP and other non-inflammatory diseases were taken as cases and controls respectively. Data on height, weight, lipid profile and fasting blood glucose levels were collected for all the patients. Body Mass Index (BMI) was calculated.

RESULTS

A total of 80 patients were recruited, 40 cases and 40 controls. The mean values for all the lipid and glucose parameters were high in cases as compared to controls with significant p-values.

CONCLUSION

In the present study metabolic derangements were seen in patients with LP.

摘要

引言

先前的研究已证实银屑病与代谢综合征之间存在关联。扁平苔藓(LP)也是一种与银屑病在形态学上相关的慢性炎症性疾病,少数研究表明LP存在代谢紊乱的关联。

目的

研究LP中代谢紊乱的关联。

材料与方法

进行了为期一年的前瞻性病例对照研究。将年龄和性别匹配的LP患者和其他非炎症性疾病患者分别作为病例组和对照组。收集了所有患者的身高、体重、血脂谱和空腹血糖水平数据。计算了体重指数(BMI)。

结果

共招募了80名患者,40例病例和40例对照。与对照组相比,病例组所有脂质和血糖参数的平均值均较高,p值具有显著性。

结论

在本研究中,LP患者出现了代谢紊乱。

相似文献

1
Metabolic Derangements in Lichen Planus - A Case Control Study.扁平苔藓中的代谢紊乱——一项病例对照研究
J Clin Diagn Res. 2016 Nov;10(11):WC01-WC03. doi: 10.7860/JCDR/2016/21993.8818. Epub 2016 Nov 1.
2
Comorbidities in Lichen Planus: A Case-control Study in Indian Patients.扁平苔藓的合并症:印度患者的一项病例对照研究。
Indian Dermatol Online J. 2019 Jan-Feb;10(1):34-37. doi: 10.4103/idoj.IDOJ_48_18.
3
Prevalence of Metabolic Syndrome in Patients with Mucosal Lichen Planus: A Case-Control Study.黏膜性扁平苔藓患者代谢综合征的患病率:一项病例对照研究。
Am J Clin Dermatol. 2015 Oct;16(5):439-45. doi: 10.1007/s40257-015-0142-8.
4
Dyslipidemia in Lichen Planus: A Case-control Study.扁平苔藓中的血脂异常:一项病例对照研究。
Sisli Etfal Hastan Tip Bul. 2020 Mar 25;54(1):62-66. doi: 10.14744/SEMB.2018.48108. eCollection 2020.
5
Cross-sectional Study Shows an Association between Paediatric Lichen Planus and Dyslipidemia.横断面研究显示儿童扁平苔藓与血脂异常之间存在关联。
Indian J Dermatol. 2022 Sep-Oct;67(5):531-534. doi: 10.4103/ijd.ijd_100_22.
6
High Incidence of Metabolic Syndrome Components in Lichen Planus Patients: A Prospective Cross-Sectional Study.扁平苔藓患者代谢综合征组分的高发率:一项前瞻性横断面研究。
Int J Clin Pract. 2022 Jan 31;2022:7184678. doi: 10.1155/2022/7184678. eCollection 2022.
7
Eruptive Lichen Planus, a Marker of Metabolic Syndrome.发疹性扁平苔藓,一种代谢综合征的标志物。
Indian J Dermatol. 2019 Jul-Aug;64(4):299-302. doi: 10.4103/ijd.IJD_553_17.
8
Cardiovascular and Metabolic Risk Assessment in Patients with Lichen Planus: A Tertiary Care Hospital-based Study from Northern India.扁平苔藓患者的心血管和代谢风险评估:一项来自印度北部一家三级护理医院的研究
Indian Dermatol Online J. 2020 Mar 9;11(2):158-166. doi: 10.4103/idoj.IDOJ_228_19. eCollection 2020 Mar-Apr.
9
Lichen Planus and Metabolic Syndrome: Is There a Relation?扁平苔藓与代谢综合征:存在关联吗?
Indian Dermatol Online J. 2019 Aug 28;10(5):555-559. doi: 10.4103/idoj.IDOJ_499_18. eCollection 2019 Sep-Oct.
10
Alterations in Lipid Metabolism and Antioxidant Status in Lichen Planus.扁平苔藓患者脂质代谢及抗氧化状态的改变
Indian J Dermatol. 2015 Sep-Oct;60(5):439-44. doi: 10.4103/0019-5154.159624.

引用本文的文献

1
Comparative Analysis of Sociodemographic, Clinical Features, Laboratory Findings, and Treatment Protocols in Generalized and Localized Cutaneous Lichen Planus.泛发性和局限性皮肤扁平苔藓的社会人口学、临床特征、实验室检查结果及治疗方案的比较分析
Cureus. 2025 Feb 16;17(2):e79081. doi: 10.7759/cureus.79081. eCollection 2025 Feb.
2
Lipid Aberrations in Lichen Planus.扁平苔藓中的脂质异常
Metabolites. 2022 Oct 22;12(11):1008. doi: 10.3390/metabo12111008.
3
High Incidence of Metabolic Syndrome Components in Lichen Planus Patients: A Prospective Cross-Sectional Study.扁平苔藓患者代谢综合征组分的高发率:一项前瞻性横断面研究。
Int J Clin Pract. 2022 Jan 31;2022:7184678. doi: 10.1155/2022/7184678. eCollection 2022.
4
Cardiovascular and Metabolic Risk Assessment in Patients with Lichen Planus: A Tertiary Care Hospital-based Study from Northern India.扁平苔藓患者的心血管和代谢风险评估:一项来自印度北部一家三级护理医院的研究
Indian Dermatol Online J. 2020 Mar 9;11(2):158-166. doi: 10.4103/idoj.IDOJ_228_19. eCollection 2020 Mar-Apr.
5
Comparison of serum lipid parameters between patients with classic cutaneous lichen planus and oral lichen planus.比较经典型皮肤扁平苔藓患者和口腔扁平苔藓患者的血清脂质参数。
Clin Oral Investig. 2020 Feb;24(2):719-725. doi: 10.1007/s00784-019-02961-6. Epub 2019 May 25.
6
Prevalence of Metabolic Syndrome in Patients with Lichen Planus: A Cross-sectional Study from a Tertiary Care Center.扁平苔藓患者代谢综合征的患病率:一项来自三级医疗中心的横断面研究。
Indian Dermatol Online J. 2018 Sep-Oct;9(5):304-308. doi: 10.4103/idoj.IDOJ_27_18.

本文引用的文献

1
Lichen planus and dyslipidemia: a systematic review and meta-analysis of observational studies.扁平苔藓与血脂异常:观察性研究的系统评价和荟萃分析
Int J Dermatol. 2016 May;55(5):e295-304. doi: 10.1111/ijd.13234. Epub 2016 Feb 12.
2
Lipid profile and metabolic syndrome status in patients with oral lichen planus, oral lichenoid reaction and healthy individuals attending a dental college in northern India - a descriptive study.印度北部一所牙科学院中扁平苔藓、苔藓样反应患者及健康个体的血脂谱和代谢综合征状况——一项描述性研究。
J Clin Diagn Res. 2014 Nov;8(11):ZC92-5. doi: 10.7860/JCDR/2014/9649.5188. Epub 2014 Nov 20.
3
Cardiovascular risk factors in patients with lichen planus.扁平苔藓患者的心血管危险因素。
Am J Med. 2011 Jun;124(6):543-8. doi: 10.1016/j.amjmed.2010.12.025.
4
CD56 highCD16 - NK cell involvement in cutaneous lichen planus.CD56 高表达 CD16- NK 细胞参与皮肤扁平苔藓。
Eur J Dermatol. 2010 Nov-Dec;20(6):724-30. doi: 10.1684/ejd.2010.1096. Epub 2010 Oct 20.
5
Chronic inflammation in obesity and the metabolic syndrome.肥胖与代谢综合征中的慢性炎症。
Mediators Inflamm. 2010;2010. doi: 10.1155/2010/289645. Epub 2010 Jul 14.
6
Oxidative stress in lichen planus.扁平苔藓中的氧化应激
Acta Dermatovenerol Alp Pannonica Adriat. 2010;19(1):3-11.
7
Lichen planus and dyslipidaemia: a case-control study.扁平苔藓与血脂异常:一项病例对照研究。
Br J Dermatol. 2009 Sep;161(3):626-9. doi: 10.1111/j.1365-2133.2009.09235.x. Epub 2009 May 12.
8
Chemokines in the pathogenesis of lichenoid tissue reactions.趋化因子在苔藓样组织反应发病机制中的作用
J Invest Dermatol. 2009 Feb;129(2):315-9. doi: 10.1038/jid.2008.251. Epub 2008 Aug 21.
9
Lichen planus patients and stressful events.扁平苔藓患者与应激事件。
J Eur Acad Dermatol Venereol. 2008 Apr;22(4):437-41. doi: 10.1111/j.1468-3083.2007.02458.x.
10
Lipid peroxidation and antioxidant status in lichen planus.扁平苔藓中的脂质过氧化与抗氧化状态
Clin Exp Dermatol. 2007 Jul;32(4):430-4. doi: 10.1111/j.1365-2230.2007.02436.x. Epub 2007 Apr 24.