Hashba Hashim, Bifi Joy, Thyvalappil Anoop, Sridharan Rajiv, Sreenivasan Ajayakumar, Mathew Pretty
Department of Dermatology, Pariyaram Medical College, Kannur, Kerala, India.
Indian Dermatol Online J. 2018 Sep-Oct;9(5):304-308. doi: 10.4103/idoj.IDOJ_27_18.
There have been reports of association between lichen planus (LP) and metabolic syndrome and its various parameters.
To determine the prevalence of metabolic syndrome in patients with LP and to determine the association between the morphologic types of LP and metabolic syndrome.
In this cross-sectional study conducted over a period of 1 year, 70 clinically diagnosed patients with LP were included and evaluated for metabolic syndrome based on the modified National Cholesterol Education Program: Adult Treatment Panel III guidelines. Data were analyzed using Statistical Package for the Social Sciences version 17 software, and inferential statistical tools such as -test for continuous data and Chi-square test for categorical data were used.
A 35.7% prevalence of metabolic syndrome was found in patients with LP. The average duration of LP was found to be higher in patients with metabolic syndrome. There was a higher prevalence of central obesity, increased fasting blood sugar, and low high-density lipoprotein-cholesterolin patients with LP.
Metabolic syndrome was seen in 25 patients (35.7%) with LP. It is important to advise our patients to adopt healthy lifestyle choices to help prevent comorbidities and improve the general health of population. As this study was a cross-sectional study, the directionality of the association between LP and metabolic syndrome could not be assessed. Lack of controls and a small sample size are other limitations of our study.
已有报告称扁平苔藓（LP）与代谢综合征及其各项参数之间存在关联。
确定LP患者中代谢综合征的患病率，并确定LP的形态学类型与代谢综合征之间的关联。
在这项为期1年的横断面研究中，纳入70例临床诊断为LP的患者，并根据美国国家胆固醇教育计划成人治疗组第三次报告修订指南对代谢综合征进行评估。使用社会科学统计软件包第17版软件进行数据分析，并使用如连续数据的t检验和分类数据的卡方检验等推断性统计工具。
LP患者中代谢综合征的患病率为35.7%。发现代谢综合征患者的LP平均病程更长。LP患者中中心性肥胖、空腹血糖升高和高密度脂蛋白胆固醇降低的患病率更高。
25例（35.7%）LP患者存在代谢综合征。建议患者选择健康的生活方式以预防合并症并改善人群总体健康状况，这很重要。由于本研究为横断面研究，无法评估LP与代谢综合征之间关联的方向性。缺乏对照和样本量小是本研究的其他局限性。
